Targeted treatments for concussion in older adults
Randomized Controlled Trial of Targeted Treatment in Older Adults Following Concussion
This study tests whether a new targeted treatment for concussion can help older adults feel better and improve their thinking skills compared to standard care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 50 Years to 99 Years |
| Sex | All |
| Sponsor | University of Pittsburgh Academic / other |
| Locations | 1 site (Pittsburgh, Pennsylvania) |
| Trial ID | NCT05849064 on ClinicalTrials.gov |
What this trial studies
This study aims to conduct the first randomized control trial focused on targeted treatments for concussion in adults aged 50 and older. Participants will be enrolled during their first clinical visit for concussion and will undergo assessments at both their initial and follow-up visits. The study will compare the effectiveness of a targeted intervention against usual care, measuring outcomes such as symptom severity and cognitive function. By addressing the unique needs of older adults, this research seeks to establish evidence-based treatment protocols for this at-risk population.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 50 years or older who have been diagnosed with a concussion within the last 4 days to 12 months.
Not a fit: Patients with diagnosed neurological disorders or major psychiatric disorders other than depression/anxiety may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for concussion in older adults, enhancing recovery and quality of life.
How similar studies have performed: While there is limited research specifically targeting older adults with concussion, similar studies in younger populations have shown promising results, indicating potential for success in this novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 50 years of age or older * Diagnosed concussion within the last 4 days - 12 months * Must be recruited at their initial concussion appointment * Ability to read/write to complete study assessments/testing Exclusion Criteria: * Diagnosed major psychiatric disorders other than depression/anxiety (e.g., schizophrenia) * Diagnosed with moderate to severe brain injury or past brain surgery/malformations
Where this trial is running
Pittsburgh, Pennsylvania
- University of Pittsburgh — Pittsburgh, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: Anthony Kontos, PhD — University of Pittsburgh
- Study coordinator: Anthony Kontos, PhD
- Email: akontos@pitt.edu
- Phone: 412-432-3725
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.