Taiwan Obstructive Sleep Apnea Cohort
Official title: Clinical Features of Obstructive Sleep Apnea Patients With Different Phenotypes
Run by China Medical University Hospital · NCT07302685 · Data updated 2026-11-12
This project will recruit 7,000 people with obstructive sleep apnea in Taiwan to see if PSG-derived endotypes and clinical features predict future health outcomes by linking sleep tests with national health records.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 0 Years and up |
| Sex | All |
| Enrollment | 7000 (estimated) |
| Sponsor | China Medical University Hospital Academic / other |
| Locations | 1 site (Taichung, Taiwan) |
| Status | Recruiting |
| Started | April 10, 2020 |
| Main results expected | February 28, 2032 |
| Study ends | February 28, 2032 |
| Registry record updated | December 24, 2025 |
| Trial ID | NCT07302685 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults referred by physicians to the China Medical University Hospital sleep center with suspected or diagnosed obstructive sleep apnea who can complete at least six hours of polysomnography are ideal candidates.
✕Probably not a fit
Patients who are not referred to this center, cannot complete the required six hours of PSG, or cannot consent to linkage with national health records are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study will prospectively enroll 7,000 patients referred to the China Medical University Hospital sleep center from 2020–2027 and collect full-night polysomnography and clinical data, which will be linked to the National Health Insurance Research Database. Polysomnography parameters will be used to derive endotypic traits such as measures of airway collapsibility, loop gain, arousal threshold, and muscle compensation. The investigators will examine associations between clinical features, PSG-based endotypes, and subsequent health outcomes recorded in the national database. A subset of participants will be invited for additional testing including lung function, blood serum tests, arterial blood gas, and cognitive assessments to provide complementary phenotyping.
Why it matters
Potential benefit: If successful, this work could help identify patient-specific OSA endotypes that predict complications and guide more personalized treatment approaches.
How similar studies have gone: PSG-based endotyping has shown promise in smaller cohorts for characterizing OSA mechanisms, but large-scale prospective linkage to a national health database is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients who are referred to China Medical University Hospital sleep center by physicians Exclusion Criteria: -Individuals unable to complete at least 6 hours of PSG examination
Where it's running
-
China Medical University Hospital
Taichung, Taiwan, Taiwan Recruiting
Study contacts
- Study coordinator: Wan-Ju Cheng, Doctor
- Email: s871065@gmail.com
- Phone: +1872 +886422052121
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.