Tailored lifestyle changes to improve obstructive sleep apnea treatment
The Impact of Individually Tailored Lifestyle and Physical Activity Intervention on Obstructive Sleep Apnea in Overweight, CPAP-treated Patients in Finland: A Randomized Controlled Trial
This study is testing whether a personalized lifestyle program that boosts physical activity can help overweight people with obstructive sleep apnea feel better while using CPAP therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Filha ry Academic / other |
| Locations | 1 site (Jyväskylä) |
| Trial ID | NCT06382883 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of a personalized lifestyle intervention on the symptoms and severity of obstructive sleep apnea (OSA) in overweight individuals. Participants will receive an individually tailored program aimed at increasing physical activity levels while undergoing CPAP therapy. The study will assess improvements in quality of life, physical functioning, body composition, and overall health outcomes. Approximately 400,000 adults in Finland are affected by OSA, and this trial seeks to address the limitations of traditional CPAP treatment by incorporating behavioral changes.
Who should consider this trial
Good fit: Ideal candidates include overweight adults aged 18 to 70 with a physician-diagnosed moderate to severe obstructive sleep apnea who have not previously undergone CPAP treatment.
Not a fit: Patients with chronic obstructive pulmonary disease, severe comorbidities, or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the management of obstructive sleep apnea and enhance the quality of life for patients.
How similar studies have performed: Previous studies have shown positive outcomes with exercise interventions for OSA, but this tailored approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * A physician-diagnosed, moderate to severe obstructive sleep apnea * BMI \> 25 * Age 18- to 70-years * No previous CPAP-treatment Exclusion Criteria: * Chronic Obstructive Pulmonary Disease (COPD) or other severe conditions affecting nighttime oxygenation (mild asthma is acceptable), Obesity Hypoventilation Syndrome without sleep apnea. * Aggressive cancer or any other condition requiring intense treatments. * Weight-loss medication initiated less than 3 months before recruiting * Conditions severely impairing daily functioning (e.g., serious mental health issues, narcolepsy, severe comorbidities, profound fibromyalgia, musculoskeletal problems significantly limiting mobility and accordingly, participation in the intervention) * Conditions and diseases influencing the participant's ability to make independent decisions * Participants under 18 years of age * Pregnancy
Where this trial is running
Jyväskylä
- Central Finland Hospital District — Jyväskylä, Finland (Recruiting)
Study contacts
- Principal investigator: Tuula Vasankari — Filha ry (Finnish Lung Health Association)
- Study coordinator: Hanna Renkola
- Email: hanna.renkola@filha.fi
- Phone: +358504009490
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.