Tailored anti-inflammatory diet for Hispanics with ulcerative colitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effects of a tailored anti-inflammatory diet that includes traditional Hispanic foods on achieving disease remission in Hispanic/Latino patients with ulcerative colitis. Participants will receive catered meals, dietary guidance, and counseling sessions to support adherence to the diet. The study will also investigate biomarkers that may indicate the effectiveness of the dietary intervention. By focusing on culturally relevant foods, the study seeks to enhance dietary compliance and improve health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Documented diagnosis with ulcerative colitis from medical records.
* Self-Identify as American
* Ages 16-75
* SCCAI between 3-9 (no greater than 12 bowel movements a day)
* Fecal calprotectin \> 150mg/dl.
* On stable medications for their disease for the past 3 months
* Likeability of American foods (sandwiches, BBQ or grilled meats and vegetables, baked potatoes, smoothies, salmon, oatmeal, avocado, soups)
* No recent Inflammatory Bowel Disease (IBD) related hospitalization in the last month.

Exclusion Criteria:

* Diagnosis of Crohn's Disease (CD).
* Prior ileoanal anastomosis (J-pouch) or diversion
* No recent hospitalizations on the last 4 weeks
* No Clostridium difficile or enteric infections on the last 4 weeks
* No use of probiotics on the last 4 weeks
* Patients following the specific carbohydrate diet or mediterranean diet or anti-inflammatory diet
* No active cancer or conditions limiting their ability to follow a diet (heart failure, end stage renal disease)
* Pregnancy, breastfeeding or planning to become pregnant during study period
* Use of Total Parenteral Nutrition at the time of screening and during the study period
* Other significant or life-threatening co-morbidities
* The need for antibiotic use during the study period
* Adults unable to consent
* Ages less than 16 and \> 75 years old
* Prisoners

Where it's running

• University of Miami Health System
  Miami, Florida, United States Recruiting

Study contacts

• Principal investigator: Oriana Damas, MD, MSCTI — University of Miami Health System
• Study coordinator: Oriana Damas, MD, MSCTI
• Email: omazorra@med.miami.edu
• Phone: 305 243-6405

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.