Sustaining youth-friendly HIV self-testing in Nigerian communities.
Sustaining Innovative Tools to Expand Youth-Friendly HIV Self-Testing
This project will test whether youth-designed strategies help keep HIV self-testing and prevention services available and linked to care for adolescents and young adults (14–24) in Nigerian communities.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1216 (estimated) |
| Ages | 14 Years to 24 Years |
| Sex | All |
| Sponsor | Washington University School of Medicine Academic / other |
| Locations | 1 site (Yaba, Lagos) |
| Trial ID | NCT07072481 on ClinicalTrials.gov |
What this trial studies
The project uses participatory methods—an open call, designathon, and a hybrid bootcamp—to engage young people and community-based organizations in creating sustainment strategies for HIV self-testing (HIVST) and youth-friendly prevention services. Ideas from hundreds of youth submissions were refined into team-based proposals and combined into an enhanced sustainability strategy. In a hybrid type 2 implementation-effectiveness, cluster-randomized parallel-group design, community sites are randomized to standard 4YBY implementation versus the enhanced youth-designed sustainment approach. The trial measures whether the enhanced approach improves sustained HIVST availability, linkage to PrEP and youth-friendly clinical services, and retention in prevention programs.
Who should consider this trial
Good fit: Ideal participants are HIV-negative adolescents and young adults aged 14–24 who meet PrEP-eligibility or report condomless sex in the past six months, have no prior PrEP use, reside in the recruitment city, can consent in English or Pidgin, and can provide a contact phone number.
Not a fit: People under 14 or over 24, those living with HIV, those with prior PrEP use, or individuals who cannot consent, lack a contact phone, or do not reside in the study LGAs are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the enhanced youth-designed strategies could increase sustained access to HIV self-testing, improve linkage to PrEP and youth-friendly services, and reduce HIV risk among adolescents and young adults.
How similar studies have performed: The work builds on prior 4YBY projects led by the investigators that showed promising youth engagement and feasibility, but applying combined participatory sustainment strategies across community sites at scale is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 14-24 * Condomless anal or vaginal sex in the past six months Meet PrEP-eligibility criteria according to Nigerian guidelines (sex worker, MSM, person who uses drugs, partner with HIV, or sexually exposed youth, or engagement in transactional sex) * No history of prior PrEP use * HIV negative based on fourth-generation test * Current resident of the recruitment city with plans to stay in city for the next 12-24 months * Able to complete a written survey in English (the national language of Nigeria) or Pidgin English * All participants must agree to an informed consent and provide their cell mobile number for follow-up and retention Exclusion Criteria: * Younger than 14 and older than 24 * Inability to comply with the study protocol * Illness, cognitive impairment or threatening behavior with acute risk to self or others * No informed consent * No contact phone number * Do not reside in any of the LGAs
Where this trial is running
Yaba, Lagos
- Nigerian Institute of Medical Research — Yaba, Lagos, Nigeria (Recruiting)
Study contacts
- Principal investigator: Juliet Iwelunmor, PhD — Washington University School of Medicine
- Study coordinator: Juliet Iwelunmor, PhD
- Email: ijuliet@wustl.edu
- Phone: 2405280123
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.