Survey of ALDH Gene Family in Patients with Peripheral Artery Disease or Heart Issues
Official title: The Prevalence Survey of ALDH Gene Family in Patients With Peripheral Arterial Occlusive Disease or Acute Coronary Syndrome
Run by Chimei Medical Center · NCT05078814 · Data updated 2026-11-12
This study is trying to see how common a specific gene deficiency is in people with heart problems or poor circulation, especially in the Asian community, to understand its impact on their health.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Chimei Medical Center Academic / other |
| Locations | 1 site (Tainan) |
| Status | Recruiting |
| Started | March 1, 2018 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | October 15, 2021 |
| Trial ID | NCT05078814 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 20 and older who have been diagnosed with Peripheral Artery Occlusive Disease or Acute Coronary Syndrome.
✕Probably not a fit
Patients who refuse to participate in the study will not benefit from its findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the prevalence of the ALDH2 gene deficiency in patients diagnosed with Peripheral Artery Occlusive Disease (PAOD) or Acute Coronary Syndrome (ACS). It focuses on understanding the genetic factors that may contribute to cardiovascular health issues, particularly in the Asian population where ALDH2 deficiency is notably prevalent. The study will utilize various diagnostic methods, including the ankle-brachial index and imaging techniques, to confirm the conditions of the participants. By gathering data on the prevalence of this genetic variant, the study seeks to highlight its potential implications for patient outcomes.
Why it matters
Potential benefit: If successful, this study could enhance understanding of genetic risk factors in cardiovascular diseases, leading to better prevention and treatment strategies.
How similar studies have gone: Previous studies have indicated significant associations between ALDH2 deficiency and cardiovascular risks, suggesting that this approach has a foundation in existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age≧20 y/o 2. Using ankle-brachial index (ABI)\< 0.9, angiography, vascular duplex, CAT scan or cardiologists'impression to confirm the diagnosis of PAOD 3. Clinical presentation of claudication 4. diagnosis of ACS Exclusion Criteria: * If the patient refuses to be included in this study
Where it's running
-
Wei-Ting Chang
Tainan, Taiwan Recruiting
Study contacts
- Study coordinator: Wei-Ting Chang
- Email: cmcvecho2@gmail.com
- Phone: +886-6-2812811
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.