Clinical trial Recruiting at 1 site Observational Ages 20 and up

Survey of ALDH Gene Family in Patients with Peripheral Artery Disease or Heart Issues

Official title: The Prevalence Survey of ALDH Gene Family in Patients With Peripheral Arterial Occlusive Disease or Acute Coronary Syndrome

Run by Chimei Medical Center · NCT05078814 · Data updated 2026-11-12

This study is trying to see how common a specific gene deficiency is in people with heart problems or poor circulation, especially in the Asian community, to understand its impact on their health.

More Acute Coronary Syndrome trials

Quick facts

Study typeObservational
Ages20 Years and up
SexAll
Enrollment600 (estimated)
SponsorChimei Medical Center
Academic / other
Locations1 site (Tainan)
StatusRecruiting
StartedMarch 1, 2018
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedOctober 15, 2021
Trial IDNCT05078814 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 20 and older who have been diagnosed with Peripheral Artery Occlusive Disease or Acute Coronary Syndrome.

Probably not a fit

Patients who refuse to participate in the study will not benefit from its findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the prevalence of the ALDH2 gene deficiency in patients diagnosed with Peripheral Artery Occlusive Disease (PAOD) or Acute Coronary Syndrome (ACS). It focuses on understanding the genetic factors that may contribute to cardiovascular health issues, particularly in the Asian population where ALDH2 deficiency is notably prevalent. The study will utilize various diagnostic methods, including the ankle-brachial index and imaging techniques, to confirm the conditions of the participants. By gathering data on the prevalence of this genetic variant, the study seeks to highlight its potential implications for patient outcomes.

Why it matters

Potential benefit: If successful, this study could enhance understanding of genetic risk factors in cardiovascular diseases, leading to better prevention and treatment strategies.

How similar studies have gone: Previous studies have indicated significant associations between ALDH2 deficiency and cardiovascular risks, suggesting that this approach has a foundation in existing research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age≧20 y/o
2. Using ankle-brachial index (ABI)\< 0.9, angiography, vascular duplex, CAT scan or cardiologists'impression to confirm the diagnosis of PAOD
3. Clinical presentation of claudication
4. diagnosis of ACS

Exclusion Criteria:

* If the patient refuses to be included in this study

Where it's running

  • Wei-Ting Chang
    Tainan, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.