Surgical check: Can intra-articular cages help fix reducible atlantoaxial dislocation?
Official title: A Randomized Controlled Trial for Surgical Treatment of Reducible Atlantoaxial Dislocation
Run by Xuanwu Hospital, Beijing · NCT06003491 · Data updated 2026-11-12
This trial tests whether placing intra-articular cages during surgery can better reduce and fuse reducible atlantoaxial dislocations in eligible patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 164 (estimated) |
| Sponsor | Xuanwu Hospital, Beijing Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | July 29, 2024 |
| Main results expected | February 2028 |
| Study ends | February 2028 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT06003491 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with CT-confirmed reducible atlantoaxial dislocation who consent to follow-up and plan to undergo the proposed operation.
✕Probably not a fit
Patients with non-reducible dislocations, traumatic or rheumatoid etiologies, prior occipitocervical surgery, or other serious illnesses may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized study compares different surgical strategies for reducible atlantoaxial dislocation using intra-articular cages. Participants must have CT-confirmed reducible dislocations and agree to follow-up, with exclusions for traumatic or rheumatoid etiologies and prior occipitocervical surgeries. The aim is to compare reduction and fusion rates between approaches and determine which method provides more reliable outcomes. The trial is conducted at Xuanwu Hospital, Capital Medical University in Beijing. Outcomes will inform whether the intra-articular cage technique offers a superior option for this condition.
Why it matters
Potential benefit: If successful, patients may experience more reliable restoration of alignment and higher fusion success after surgery.
How similar studies have gone: Previous modifications of posterior distraction techniques showed promise but have not proven superiority in randomized comparisons.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * CT indicated atlantoaxial dislocation Agree with the operation plan Agree to be followed up Exclusion Criteria: * The pathology is traumatic or RA Underwent operations in occipital-cervical region before With mortal diseases Without ability to sign papers
Where it's running
-
Xuanwu Hospital, Capital Medical University
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Zan Chen, MD
- Email: chenzan66@163.com
- Phone: +8613911712120
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.