Multicenter Registry of Intracranial Dural Arteriovenous Fistulas in China
Official title: Dural Arteriovenous Fistulas Registry, Evaluation, and Management Study in China (DREAM)
Run by Xuanwu Hospital, Beijing · NCT07604688 · Data updated 2026-11-12
This study will collect and analyze data from many hospitals in China to see how common intracranial dural AV fistulas are, how they’re treated, and what outcomes look like for patients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10050 (estimated) |
| Sponsor | Xuanwu Hospital, Beijing Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | May 18, 2026 |
| Main results expected | February 28, 2030 |
| Study ends | February 28, 2030 |
| Registry record updated | June 4, 2026 |
| Trial ID | NCT07604688 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults diagnosed with IDAVF or SDAVF by DSA at participating centers, with complete medical and imaging records, and (for the prospective cohort) consent provided.
✕Probably not a fit
Patients without registered data, without adequate imaging, or with non-dural vascular malformations are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a multicenter registry that combines retrospective and prospective data from over 60 core hospitals across seven regions in China. It aims to describe incidence trends and current treatment patterns for intracranial and spinal dural arteriovenous fistulas, using digital subtraction angiography for diagnosis. The retrospective phase covers patients diagnosed from 2015 to 2025, while the prospective phase enrolls patients from 2025 to 2030, capturing baseline characteristics, treatment data, and outcomes such as obliteration, recurrence, and prognosis. The study will create a nationwide database to support observational analyses of management and outcomes in IDAVF and SDAVF.
Why it matters
Potential benefit: If successful, the registry could clarify how these fistulas occur and respond to different treatments, guiding future care and research.
How similar studies have gone: Previous regional registries have provided valuable insights into treatment patterns and outcomes for dural AV fistulas.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed with intracranial dural arteriovenous fistula (IDAVF) or spinal dural arteriovenous fistula (SDAVF) by cerebral or spinal digital subtraction angiography (DSA) * Patients treated or evaluated at participating centers during the study period * Availability of complete clinical and imaging records, including baseline information, treatment records, and DSA images * For the prospective cohort, written informed consent signed by the patient or legal representative Exclusion Criteria: * Patients with facial or scalp arteriovenous fistulas * Patients with non-dural vascular malformations or non-arteriovenous fistula vascular diseases, including cavernous malformations or venous malformations
Where it's running
-
Xuanwu Hospital
Beijing, China Recruiting
Study contacts
- Study coordinator: Xin Su, M.D
- Email: 1258940078@qq.com
- Phone: 86-18210685023
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
NAIF 2.0: See if glymphatic flow changes after dAVF treatment
This study tests whether the brain’s waste-clearance system changes after endovascular treatment for intracranial dural arteriovenous fistulas in adults.
-
International registry of spinal dural arteriovenous fistula outcomes
This registry will collect treatment and outcome data from people with spinal dural arteriovenous fistulas to see which treatments and factors relate to recovery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.