Surgical and antibiotic treatment for pressure ulcers linked to osteomyelitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients with neuromotor disabilities who are at high risk for osteomyelitis-associated pressure ulcers. It aims to evaluate the effectiveness of a one-stage surgical management approach, which includes bone shaving and flap coverage, followed by tailored antibiotic treatment. Patients will be monitored post-surgery at 30 or 45 days and again at 12 months to assess outcomes and identify factors influencing treatment success or failure. Data will be collected from medical records, covering various clinical and physiological parameters.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients \>= 18 years old ;
* Treated in the Perioperative Disability Unit (UPOH) of the Physical Medicine and Rehabilitation Department of our university hospital;
* Admitted for the treatment of an osteomyelitis-associated pressure ulcer by surgical flap;
* Having a neuromotor disability;
* No opposition to be enrolled in the study from the patient, or from a legally authorized close relative if the patient's state of health does not allow it;
* Affiliation to a social security scheme.

Exclusion Criteria:

* Under court protection.

Where it's running

• Department of Physical Medicine and Rehabilitation, Raymond Poincaré Hospital, AP-HP
  Garches, France Recruiting

Study contacts

• Principal investigator: François Genêt, MD-PhD — Department of Physical Medicine and Rehabilitation, Raymond Poincaré Hospital, AP-HP, 92380 Garches, France
• Study coordinator: François Genêt, MD-PhD
• Email: françois.genet@aphp.fr
• Phone: + 33 1 47 10 70 82

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.