Surgery for Adolescent Idiopathic Scoliosis

Spine Surgery for Lenke 1 Adolescent Idiopathic Scoliosis: a Pilot Study

NA · Istituto Ortopedico Rizzoli · NCT06396286

This study is testing a new type of surgery for teenagers with scoliosis to see if using a single rod can correct their spine while helping them recover better and keep their movement.

Quick facts

PhaseNA
Study typeInterventional
Enrollment20 (estimated)
Ages12 Years to 21 Years
SexAll
SponsorIstituto Ortopedico Rizzoli (other)
Locations1 site (Bologna)
Trial IDNCT06396286 on ClinicalTrials.gov

What this trial studies

This clinical trial focuses on the surgical correction of adolescent idiopathic scoliosis (AIS) in patients aged 12 to 21 with specific curve characteristics. The study aims to evaluate the effectiveness of a single rod intervention in correcting the spinal deformity while minimizing invasiveness and preserving spinal mobility. Participants will undergo surgery to correct their thoracic scoliotic curve, with careful monitoring of preoperative and postoperative outcomes. The trial seeks to improve surgical techniques and patient recovery in adolescents with AIS.

Who should consider this trial

Good fit: Ideal candidates are adolescents aged 12 to 21 diagnosed with Lenke type I thoracic scoliotic curves and a Cobb angle between 40° and 70°.

Not a fit: Patients with scoliosis of a different etiology, those with Cobb angles greater than 70°, or those who have previously undergone scoliosis surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved surgical outcomes and quality of life for adolescents with scoliosis.

How similar studies have performed: Other studies have shown success with similar surgical interventions for scoliosis, but this specific approach using a single rod is being evaluated for its unique benefits.

Eligibility criteria

Show full inclusion / exclusion criteria
INCLUSION CRITERIA:

* Diagnosis of AIS;
* Male and female sex;
* Age between 12 and 21;
* Thoracic scoliotic curve, type I according to Lenke's classification;
* Preoperative radiographic range of the main scoliotic curve between 40° and 70° Cobb;
* Reducibility of the curve on bending radiographs by 30%;
* Signature of the informed consent of patients/parents to actively participate in the study and clinical follow-up.

EXCLUSION CRITERIA:

* Scoliosis with an etiology different from AIS;
* pre-operative COBB \> 70°;
* Patients already treated surgically for scoliosis;
* Location of the scoliotic curve: Lenke 2-6;
* Patients who do not fall within the parameters described;
* Patients unable to express consent or carry out follow-ups;
* Language barrier;
* Pregnant women.

Where this trial is running

Bologna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Scoliosis, Spine Deformity, Adolescent Idiopathic Scoliosis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.