Support program for pregnant women and mothers facing intimate partner violence

MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence: Randomized Trial

Not applicable Interventional Michigan State University · NCT05106361

This study is testing a new support program for pregnant women and mothers who have experienced intimate partner violence to see if it can help reduce their depression and PTSD symptoms while preventing further violence.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexFemale
SponsorMichigan State University Academic / other
Locations1 site (Flint, Michigan)
Trial IDNCT05106361 on ClinicalTrials.gov

What this trial studies

This exploratory research aims to develop a larger randomized controlled trial evaluating the effectiveness of the MOSAIC Plus intervention, which integrates interpersonal therapy principles to help pregnant women and mothers of young children who have experienced intimate partner violence (IPV). The study will enroll participants who report IPV in the past six months and have elevated symptoms of depression or PTSD. The intervention will last for six months and focuses on reducing depressive and PTSD symptoms while preventing further IPV. The study addresses a significant public health issue, as IPV is linked to severe mental health consequences and poor health outcomes for mothers and their children.

Who should consider this trial

Good fit: Ideal candidates are pregnant women or mothers of children under five who have experienced intimate partner violence in the past six months and exhibit elevated depressive or PTSD symptoms.

Not a fit: Patients who do not report experiencing intimate partner violence or do not have elevated depressive or PTSD symptoms may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve mental health outcomes for pregnant women and mothers experiencing IPV, reducing symptoms of depression and PTSD.

How similar studies have performed: While there are few interventions targeting IPV among this population, the MOSAIC intervention has shown promise, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Pregnant and/or are mothers of children under 5 and r
* Report IPV experiences in the past 6 months (as assessed by Composite Abuse Scale)
* Aged 18 or above,
* Have elevated depressive and/or PTSD symptoms as assessed by Patient Health Questionnaire (PHQ-9) with a cutoff point of ≥9, and/or the Davidson Trauma Scale (DTS) with a cut-off point of ≥40.

Exclusion Criteria:

* Cannot provide the name and contact information of at least two locator persons,
* Do not have access to any telephone,
* Cannot understand English well enough to understand the consent form or assessment instruments when they are read aloud

Where this trial is running

Flint, Michigan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Intimate Partner ViolenceDepressionPost Traumatic Stress DisorderIntimate partner violenceWomenMothersPregnant
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.