Support for adolescents living with HIV in South Africa
Official title: Interactive Transition Support for Adolescents Living With HIV Comparing Virtual and In-person Delivery Through a Stepped-wedge Cluster Randomized Clinical Trial in South Africa
Run by Emory University · NCT06035445 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study tests if in-person and mobile health support can help teenagers with HIV in South Africa better transition to adult healthcare services and stay healthy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years to 19 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Emory University Academic / other |
| Locations | 1 site (Congella) |
| Trial ID | NCT06035445 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adolescents aged 15 to 19 years who are living with perinatally-acquired HIV and have been on antiretroviral therapy for at least six months.
✕Probably not a fit
Patients who are unable to read or speak English or Zulu, or those with severe mental or physical illnesses that prevent informed consent, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial evaluates the effectiveness of in-person and mobile health interventions designed to assist adolescents living with HIV in transitioning from pediatric to adult healthcare services. It focuses on adolescents aged 15 to 19 in KwaZulu-Natal, South Africa, who have low readiness for this transition. The study compares these interventions against standard care to determine their impact on retention in care and viral suppression. Given the high number of adolescents living with HIV in South Africa, this research aims to address a critical gap in healthcare support during a vulnerable transition period.
Why it matters
Potential benefit: If successful, this study could significantly improve retention in care and health outcomes for adolescents living with HIV.
How similar studies have gone: Other studies have shown success with similar transition interventions for adolescents living with HIV, indicating a promising approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria for Adolescent Participants: * Aged 15 to 19 years at enrollment * Living with perinatally-acquired HIV * Receiving ART for at least 6 months * Aware of their HIV status * Scoring low to intermediate on transition readiness assessment (intervention cohort only) Inclusion Criteria for Healthcare Providers: * Profession as a healthcare provider * Working at one of the designated clinics * Involvement with adolescents before, during or after transition to adult care Exclusion Criteria for all participants: * Inability to read and/or speak English or Zulu * Severe mental or physical illness preventing participation in informed consent activities * Anticipated move out of clinic area in the next 12 months
Where it's running
-
King Edward VIII Hospital
Congella, South Africa Recruiting
Study contacts
- Principal investigator: Brian C Zanoni, MD, MPH — Emory University
- Study coordinator: Brian C Zanoni, MD, MPH
- Email: brian.christopher.zanoni@emory.edu
- Phone: 404-727-0284
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.