Supplementing premature babies' enteral feeding with olive oil
The Effect of Enteral Organic Extra Virgin Olive Oil Supplementation in Premature Babies on Postnatal Growth and Premature Morbidities
This study is testing if adding olive oil to the diets of premature babies can improve their health and growth compared to those who don't get the oil.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 14 Days to 40 Days |
| Sex | All |
| Sponsor | Bursa City Hospital Government |
| Locations | 1 site (Bursa) |
| Trial ID | NCT06072625 on ClinicalTrials.gov |
What this trial studies
This interventional study involves two groups of premature babies, with 40 infants in each group. The intervention group will receive 1 ml/kg/day of extra virgin organic olive oil after achieving full enteral feeding, while the control group will not receive the supplement. Blood samples will be collected to measure antioxidant capacity and malondialdehyde levels at various points during the study. Growth parameters and lipid profiles will be monitored, and outcomes related to retinopathy of prematurity (ROP), bronchopulmonary dysplasia (BPD), and necrotizing enterocolitis (NEC) will be evaluated at the end of the study.
Who should consider this trial
Good fit: Ideal candidates for this study are premature babies born at 32 weeks gestation or less who can tolerate full enteral feeding by the end of the second week.
Not a fit: Patients with congenital or genetic anomalies will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance the nutritional support and overall health outcomes of premature infants.
How similar studies have performed: While the specific use of olive oil supplementation in this context may be novel, similar studies on nutritional interventions in premature infants have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Premature babies born at 32 weeks or less * Babies who tolerate full enteral feeding at the before end of the second week * Babies given consent by their parents - Exclusion Criteria: * Having a congenital or genetic anomaly
Where this trial is running
Bursa
- Bursa City Hospital — Bursa, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Ayten Erdoğan Ordu, MD
- Email: aytenli21@hotmail.com
- Phone: +905389429336
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.