Sublingual melatonin before cataract surgery in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 60 and older scheduled for unilateral cataract surgery under local anesthesia will receive either sublingual melatonin or a matching placebo before the procedure. Eligible participants are ASA physical status I–III and must be able to complete study questionnaires. The trial will record patient-reported anxiety and sedation, as well as objective hemodynamic measures like blood pressure and heart rate and any adverse events. Results will compare anxiety relief, sedation levels, and safety between the melatonin and placebo groups.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • Age ≥ 60 years

  * American Society of Anesthesiologists (ASA) physical status I-III
  * Scheduled for unilateral cataract surgery under local anesthesia
  * Ability to understand and complete study-related questionnaires

Exclusion Criteria:

* • Known allergy or hypersensitivity to melatonin

  * Chronic use of sedatives, hypnotics, or anxiolytics
  * History of sleep disorders or psychiatric illness
  * Visual or hearing impairment that would hinder communication
  * Emergency surgery or anticipated intraoperative complications

Where it's running

• Al-Azhar University
  Baghdad, Baghdad Governorate, Iraq Recruiting
• Al-Azhar University
  Cairo, Egypt, Egypt Not yet recruiting

Study contacts

• Principal investigator: Neveen A Kohaf, PhD — Al-Azhar University
• Study coordinator: Neveen A Kohaf, PhD
• Email: nevenabdo@azhar.edu.eg
• Phone: +201060383012

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.