Study on risk factors and outcomes in patients with tricuspid regurgitation
Tricuspid RegurgitAtion rIsk modeL Study (TRAIL Study)
This study looks at patients with tricuspid regurgitation in the hospital to see what factors affect their health outcomes and how likely they are to face serious issues or death.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Sun Yat-sen University Academic / other |
| Locations | 7 sites (Guangzhou, Guangdong and 6 other locations) |
| Trial ID | NCT06926959 on ClinicalTrials.gov |
What this trial studies
This multicenter cohort study focuses on patients diagnosed with tricuspid regurgitation during hospitalization. It aims to evaluate prognostic risk factors associated with this condition and construct predictive models based on follow-up observations. The primary outcome is all-cause mortality, while secondary outcomes include cardiovascular events. The study will gather data from multiple hospitals to enhance the understanding of tricuspid regurgitation outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who have been diagnosed with tricuspid regurgitation during hospitalization.
Not a fit: Patients who are unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve risk assessment and management strategies for patients with tricuspid regurgitation.
How similar studies have performed: While there have been studies on tricuspid regurgitation, this specific approach to developing a risk model is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged over 18 yrs. * Patients diagnosed with tricuspid regurgitation during hospitalization. Exclusion Criteria: * Patients unable to provide informed consent.
Where this trial is running
Guangzhou, Guangdong and 6 other locations
- The First Affiliated Hospital of Sun Yat-sen Univerity — Guangzhou, Guangdong, China (Recruiting)
- Third Affiliated Hospital, Sun Yat-Sun University, — Guangzhou, Guangdong, China (Active_not_recruiting)
- Jieyang People's Hospital — Jieyang, Guangdong, China (Active_not_recruiting)
- Second Affiliated Hospital of Shantou University Medical College — Shantou, Guangdong, China (Active_not_recruiting)
- Eighth Affiliated Hospital, Sun Yat-Sen University — Shenzhen, Guangdong, China (Active_not_recruiting)
- Affiliated Hospital of Guangdong Medical University — Zhanjiang, Guangdong, China (Active_not_recruiting)
- Zhongshan People's Hospital — Zhongshan, Guangdong, China (Active_not_recruiting)
Study contacts
- Study coordinator: Xiaodong Zhuang
- Email: zhuangxd3@mail.sysu.edu.cn
- Phone: +8613760755035
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.