Clinical trial Recruiting at 1 site Observational Ages 18 and up

Study on risk factors and outcomes in patients with tricuspid regurgitation

Official title: Tricuspid RegurgitAtion rIsk modeL Study (TRAIL Study)

Run by Sun Yat-sen University · NCT06926959 · Data updated 2026-11-12

This study looks at patients with tricuspid regurgitation in the hospital to see what factors affect their health outcomes and how likely they are to face serious issues or death.

More Tricuspid Regurgitation trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment3000 (estimated)
SponsorSun Yat-sen University
Academic / other
Locations7 sites (Guangzhou, Guangdong and 6 other locations)
StatusRecruiting
StartedJune 15, 2016
Main results expectedJune 15, 2030
Study endsJune 15, 2030
Registry record updatedApril 15, 2025
Trial IDNCT06926959 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old who have been diagnosed with tricuspid regurgitation during hospitalization.

Probably not a fit

Patients who are unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter cohort study focuses on patients diagnosed with tricuspid regurgitation during hospitalization. It aims to evaluate prognostic risk factors associated with this condition and construct predictive models based on follow-up observations. The primary outcome is all-cause mortality, while secondary outcomes include cardiovascular events. The study will gather data from multiple hospitals to enhance the understanding of tricuspid regurgitation outcomes.

Why it matters

Potential benefit: If successful, this study could improve risk assessment and management strategies for patients with tricuspid regurgitation.

How similar studies have gone: While there have been studies on tricuspid regurgitation, this specific approach to developing a risk model is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged over 18 yrs.
* Patients diagnosed with tricuspid regurgitation during hospitalization.

Exclusion Criteria:

* Patients unable to provide informed consent.

Where it's running

  • The First Affiliated Hospital of Sun Yat-sen Univerity
    Guangzhou, Guangdong, China
    Recruiting
  • Third Affiliated Hospital, Sun Yat-Sun University,
    Guangzhou, Guangdong, China
    Active not recruiting
  • Jieyang People's Hospital
    Jieyang, Guangdong, China
    Active not recruiting
  • Second Affiliated Hospital of Shantou University Medical College
    Shantou, Guangdong, China
    Active not recruiting
  • Eighth Affiliated Hospital, Sun Yat-Sen University
    Shenzhen, Guangdong, China
    Active not recruiting
  • Affiliated Hospital of Guangdong Medical University
    Zhanjiang, Guangdong, China
    Active not recruiting
Show 1 more location
  • Zhongshan People's Hospital
    Zhongshan, Guangdong, China
    Active not recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.