Clinical trial Recruiting at 1 site Observational Women only

Study on mental health issues during and after pregnancy in Guangzhou

Official title: Peripartum Mental Health Cohort Study in Guangzhou

Run by Guangzhou Women and Children's Medical Center · NCT04499066 · Data updated 2026-11-12

This study looks at how common mental health issues like depression and anxiety are for pregnant women in Guangzhou, to help find ways to better support mothers and their babies.

More Depression trials

Quick facts

Study typeObservational
SexWomen only
Enrollment3000 (estimated)
SponsorGuangzhou Women and Children's Medical Center
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedFebruary 1, 2012
Main results expectedDecember 31, 2025
Study endsDecember 31, 2038
Registry record updatedSeptember 13, 2023
Trial IDNCT04499066 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are pregnant women under 20 weeks of gestation who plan to deliver at the Guangzhou Women and Children's Medical Center.

Probably not a fit

Patients with pre-existing heart disease, hypertension, diabetes, or those currently taking antidepressants may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the incidence and development of mental health problems, such as depression and anxiety, during the peripartum period among pregnant women in Guangzhou. It will collect epidemiological and clinical data, along with biological specimens, to understand the trajectory of these mental health issues and identify risk factors. The goal is to develop a comprehensive prediction model for postpartum depression and explore its adverse outcomes, ultimately improving health interventions for mothers and their children.

Why it matters

Potential benefit: If successful, this study could lead to better screening and intervention strategies for peripartum mental health issues, improving outcomes for mothers and their children.

How similar studies have gone: Other studies have shown success in understanding peripartum mental health issues, but this specific approach focusing on Chinese women is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Pregnant women with \<20 weeks of gestation
2. Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center
3. Permanent residents or families intended to remain in Guangzhou with their child for more than 3 years

Exclusion Criteria:

1. Combined with heart disease, hypertension, diabetes or hyperthyroidism
2. Taking anti-depressants and other treatments for depression
3. Participants was in infection status when the biological samples were collected

Where it's running

  • Guangzhou Women and Children's Medical Center
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

  • Principal investigator: Xiu Qiu, PhD — Guangzhou Women and Children's Medical Center
  • Study coordinator: Xiu Qiu, PhD
  • Email: qxiu0161@163.com
  • Phone: 0086 20 38367160

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.