Study on mental health issues during and after pregnancy in Guangzhou
Official title: Peripartum Mental Health Cohort Study in Guangzhou
Run by Guangzhou Women and Children's Medical Center · NCT04499066 · Data updated 2026-11-12
This study looks at how common mental health issues like depression and anxiety are for pregnant women in Guangzhou, to help find ways to better support mothers and their babies.
Quick facts
| Study type | Observational |
|---|---|
| Sex | Women only |
| Enrollment | 3000 (estimated) |
| Sponsor | Guangzhou Women and Children's Medical Center Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | February 1, 2012 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2038 |
| Registry record updated | September 13, 2023 |
| Trial ID | NCT04499066 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are pregnant women under 20 weeks of gestation who plan to deliver at the Guangzhou Women and Children's Medical Center.
✕Probably not a fit
Patients with pre-existing heart disease, hypertension, diabetes, or those currently taking antidepressants may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the incidence and development of mental health problems, such as depression and anxiety, during the peripartum period among pregnant women in Guangzhou. It will collect epidemiological and clinical data, along with biological specimens, to understand the trajectory of these mental health issues and identify risk factors. The goal is to develop a comprehensive prediction model for postpartum depression and explore its adverse outcomes, ultimately improving health interventions for mothers and their children.
Why it matters
Potential benefit: If successful, this study could lead to better screening and intervention strategies for peripartum mental health issues, improving outcomes for mothers and their children.
How similar studies have gone: Other studies have shown success in understanding peripartum mental health issues, but this specific approach focusing on Chinese women is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Pregnant women with \<20 weeks of gestation 2. Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center 3. Permanent residents or families intended to remain in Guangzhou with their child for more than 3 years Exclusion Criteria: 1. Combined with heart disease, hypertension, diabetes or hyperthyroidism 2. Taking anti-depressants and other treatments for depression 3. Participants was in infection status when the biological samples were collected
Where it's running
-
Guangzhou Women and Children's Medical Center
Guangzhou, Guangdong, China Recruiting
Study contacts
- Principal investigator: Xiu Qiu, PhD — Guangzhou Women and Children's Medical Center
- Study coordinator: Xiu Qiu, PhD
- Email: qxiu0161@163.com
- Phone: 0086 20 38367160
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Mindful Smartphone Use: A Mindfulness-Based Program for Teens with Sleep and Mood Challenges
This study tests Mindwire, a mindfulness-based program, to see if it helps teens with problematic phone use who also have depression or anxiety.
-
Tele-based wellbeing centres for women's mental health in Bangladesh
A randomized trial tests whether tele-counselling for depression and anxiety in Bangladeshi women is as effective as in-person counselling.
-
HBOT to see if it helps cognition and well‑being in first responders with prior brain injury
This study tests whether 40 hyperbaric oxygen therapy sessions can improve thinking skills and post-concussion symptoms in current or former first responders with a history of brain injury.
-
Focused ultrasound for mood and anxiety disorders
This study tests whether repeated low-intensity focused ultrasound using the ATTN201 device can help people with subsyndromal to moderate depression, anxiety, or OCD.
-
An Ultra-Brief ICBT Intervention with Personal Feedback for Depression and Anxiety
This trial tests whether adding personalized feedback about a person’s recent healthy actions to the Things You Do ultra-brief online CBT program helps adults with depression and anxiety do more healthy activities and feel better.
-
Virtual nature vs guided imagery for anxiety and well-being in hospitalized older adults
In this study, hospitalized adults 65 and older try two ways to bring nature to them: watching 360-degree nature videos on a VR headset or listening to a guided imagery audio to imagine the same scenes, to see which helps mood and anxiety during a two-week period.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.