Study on invasive bacterial diseases and their epidemiology
Official title: Epidemiological Study on Invasive Bacterial Diseases (IBD)
Run by Meyer Children's Hospital IRCCS · NCT06322290 · Data updated 2026-11-12
This study is trying to see how well new testing methods can identify serious bacterial infections in patients to help improve treatments and vaccination strategies.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Day to 70 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Meyer Children's Hospital IRCCS Academic / other |
| Locations | 38 sites (Adria and 37 other locations) |
| Status | Recruiting |
| Started | December 9, 2021 |
| Main results expected | December 30, 2031 |
| Study ends | March 30, 2032 |
| Registry record updated | March 21, 2024 |
| Trial ID | NCT06322290 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are pediatric and adult patients diagnosed with pneumococcal, meningococcal, or hemophilus invasive bacterial infections.
✕Probably not a fit
Patients with other types of bacterial infections will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on the epidemiology of invasive bacterial diseases caused by Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. It aims to improve pathogen identification through molecular diagnostic methods, which can detect bacteria even when they are not viable. By analyzing blood specimens from patients, the study seeks to characterize circulating strains and assess the impact of vaccination strategies. The findings will guide public health interventions and improve treatment and prevention strategies for these serious infections.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of diagnosing invasive bacterial diseases and inform better public health strategies, potentially reducing the incidence of these infections.
How similar studies have gone: Other studies utilizing molecular diagnostic methods for pathogen identification have shown promise, indicating that this approach is both relevant and potentially effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric and adult patients diagnosed with pneumococcal, meningococcal, and hemophilus MBI Exclusion Criteria: * Other type of bacterial infections.
Where it's running
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Immunology Laboratory Meyer Children's Hospital IRCCS
Florence, Italy Recruiting -
Ospedale di Adria
Adria, Italy Not yet recruiting -
Ospedali riuniti di Ancona
Ancona, Italy Not yet recruiting -
Ospedale di Andria
Andria, Italy Not yet recruiting -
Ospedale Giovanni XXIII
Bari, Italy Not yet recruiting -
Policlinico S.Orsola-Malpighi IRCCS
Bologna, Italy Not yet recruiting
Show 32 more locations
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Fondazione poliambulanza Brescia
Brescia, Italy Not yet recruiting -
Ospedale Giovanni XXIII
Brescia, Italy Not yet recruiting -
Ospedale di Campobasso
Campobasso, Italy Not yet recruiting -
Ospedale Camposampiero
Camposampiero, Italy Not yet recruiting -
Ospedale di Esine asst Valcamonica
Esine, Italy Not yet recruiting -
Ospedale di Feltre (AULSS 1 Dolomiti)
Feltre, Italy Not yet recruiting -
Ospedale Morgagni
Forlì, Italy Not yet recruiting -
AO Salvini di Garbagnate
Garbagnate, Italy Not yet recruiting -
Azienda sanitaria universitaria Giuliano Isontina (ASU GI)
Gorizia, Italy Not yet recruiting -
Ospedale di Magenta
Magenta, Italy Not yet recruiting -
Azienda Ospedaliera Policlinico Universitario "G. Martino"
Messina, Italy Not yet recruiting -
IRCCS San Raffaele
Milan, Italy Not yet recruiting -
AORN Santobono
Naples, Italy Not yet recruiting -
AOU Federico II di Napoli
Naples, Italy Not yet recruiting -
Ospedale di Novara
Novara, Italy Not yet recruiting -
Fondazione I.R.C.C.S. Policlinico San Matteo
Pavia, Italy Not yet recruiting -
Ospedale spirito santo di Pescara
Pescara, Italy Not yet recruiting -
Azienda sanitaria Friuli occidentale
Pordenone, Italy Not yet recruiting -
Ospedale di Macerata
Province of Macerata, Italy Not yet recruiting -
Ospedale degli infermi
Rimini, Italy Not yet recruiting -
Ospedale Pediatrico Bambin Gesù IRCCS
Roma, Italy Not yet recruiting -
Ospedale Sandro Pertini
Roma, Italy Not yet recruiting -
Ospedale San Leonardo di Salerno
Salerno, Italy Not yet recruiting -
Ospedale di Saronno
Saronno, Italy Not yet recruiting -
AOU Sassari
Sassari, Italy Not yet recruiting -
Ospedale di Scorrano
Scorrano, Italy Not yet recruiting -
ASP Trapani
Trapani, Italy Not yet recruiting -
IRCCS Materno Infantile Burlo Garofolo
Trieste, Italy Not yet recruiting -
Azienda sanitaria universitaria Friuli Centrale (ASU FC)
Udine, Italy Not yet recruiting -
Azienda ospedaliera universitaria integrata Verona
Verona, Italy Not yet recruiting -
Ospedale civile di Vibo Valentia
Vibo Valentia, Italy Not yet recruiting -
Ospedale Maggiore Carlo Alberto Pizzardi
Bologna, Ì, Italy Not yet recruiting
Study contacts
- Study coordinator: Chiara Azzari, MD
- Email: chiara.azzari@meyer.it
- Phone: 00390555662542
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.