Study on health products for improving cognitive function

Radicle Clarity™ 24: A Randomized, Double-Blind, Placebo-Controlled Direct-to-Consumer Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes

NA · Radicle Science · NCT06294431

This study is testing whether certain health products can help adults improve their concentration and mental clarity over seven weeks.

Quick facts

PhaseNA
Study typeInterventional
Enrollment2594 (estimated)
Ages21 Years to 105 Years
SexAll
SponsorRadicle Science (industry)
Drugs / interventionschemotherapy, immunotherapy
Locations1 site (Del Mar, California)
Trial IDNCT06294431 on ClinicalTrials.gov

What this trial studies

This study is a randomized, double-blind, placebo-controlled trial that evaluates the effects of health and wellness products on cognitive function and related health outcomes in adults. Participants will be recruited from the United States and will report their experiences electronically over a 7-week period. The study aims to assess whether these products can lead to meaningful improvements in concentration and cognitive clarity. Participants will not know whether they are receiving the active product or a placebo until the conclusion of the study.

Who should consider this trial

Good fit: Ideal candidates are adults aged 21 and older who seek to improve their concentration and cognitive function.

Not a fit: Patients with known cardiac dysfunction, liver or kidney disease, or those who are pregnant or breastfeeding may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into effective health products that enhance cognitive function and overall mental clarity.

How similar studies have performed: While there have been studies on cognitive enhancement products, the specific approach of this trial is relatively novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults, at least 21 years of age at the time of electronic consent, inclusive of all ethnicities, races, and gender identities. Assigned sex at birth will determine sex-specific recruitment and surveys (male vs female) employed, when needed
* Resides in the United States
* Endorses better concentration or cognitive function (fewer feelings of brain fog) as a primary desire
* Has the opportunity for at least 20% improvement in their primary health outcome
* Expresses a willingness to take a study product and not know the product identity (active or placebo) until the end of the study

Exclusion Criteria:

* Report being pregnant, trying to become pregnant, or breastfeeding
* Unable to provide a valid US shipping address and mobile phone number
* Reports current enrollment in another clinical trial
* Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day)
* Unable to read and understand English
* Reports a current and/or recent (up to 3 months ago) major illness and/or surgery that poses a known, significant safety lak
* Reports a diagnosis or cardiac dysfunction, liver or kidney disease that presents a known contraindication and/or a significant safety risk with any of the study product ingredients. NYHA (New York Heart Association) Class Ill or IV congestive heart failure, atrial fibrillation, uncontrolled arrhythmias, cirrhosis, end-stage liver disease, stage 3b or 4 chronic kidney disease, or kidney failure
* Reports taking medications that have a well-established moderate or severe interaction, posing a substantial safety risk with any of the study product ingredients. Anticoagulants, antihypertensives, anxiolytics, antidepressants, chemotherapy, immunotherapy, sedative hypnotics, seizure medications, medications that warn against grapefruit consumption, corticosteroids at doses greater than 5 mg per day, diabetic medications, oral anti-infectives (antibiotics, antifungals, antivirals) to treat an acute infection, antipsychotics, MAOls (monoamine oxidase inhibitors), or thyroid products
* Reports current use of the primary ingredient(s) and/or similar product(s) to the active study product(s)
* Lack of reliable daily access to the internet

Where this trial is running

Del Mar, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cognitive Function

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.