Clinical trial Recruiting at 1 site Observational Ages 18 and up

Study of the mechanical properties of diseased blood vessel tissues

Official title: The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

Run by University Hospital of Limerick · NCT05802706 · Data updated 2026-11-12

This study looks at the strength and properties of unhealthy blood vessel tissues from patients having surgery to see if they relate to new blood tests for heart disease.

More Vascular Diseases trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorUniversity Hospital of Limerick
Academic / other
Locations1 site (Limerick, Limerick)
StatusRecruiting
StartedJanuary 1, 2016
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2027
Registry record updatedApril 17, 2025
Trial IDNCT05802706 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients with arterial plaque who are undergoing treatment and can provide informed consent.

Probably not a fit

Patients who are unable to give informed consent or are seriously ill may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the mechanical properties of atherosclerotic plaque from human carotid and femoral arteries, as well as abdominal aortic aneurysm tissue. It aims to correlate these tissue mechanics with novel blood-based biomarkers related to cardiovascular calcification. The study involves patients undergoing standard surgical procedures for plaque removal, allowing for the collection and analysis of tissue samples without any experimental interventions. The findings could enhance understanding of vascular diseases and their biomarkers.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for vascular diseases.

How similar studies have gone: While this approach is observational and correlational, similar studies have shown promise in understanding the mechanics of vascular diseases and their relationship with biomarkers.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with arterial plaque undergoing treatment where the plaque tissue will be surgically removed as per the usual peripheral endarterectomy procedure.
* Able to provide informed consent.

Exclusion Criteria:

* Patients that are unable to give informed consent.
* Seriously ill/unconscious patients.

Where it's running

  • University Hospital Limerick
    Limerick, Limerick, Ireland
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.