Clinical trial Recruiting at 1 site Observational Ages 0 to 50

Study of early life factors affecting maternal and child health

Official title: Early Life Origins of Pediatric and Adult Diseases: Boston Birth Cohort Study

Run by Johns Hopkins Bloomberg School of Public Health · NCT03228875 · Data updated 2026-11-12

This study looks at how factors from early life affect the health of mothers and their children, focusing on women giving birth at Boston Medical Center.

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Quick facts

Study typeObservational
Ages0 Years to 50 Years
SexAll
Enrollment24000 (estimated)
SponsorJohns Hopkins Bloomberg School of Public Health
Academic / other
Locations1 site (Boston, Massachusetts)
StatusRecruiting
StartedOctober 1998
Main results expectedDecember 2028
Study endsDecember 2032
Registry record updatedSeptember 11, 2026
Trial IDNCT03228875 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include mothers delivering singleton live infants at Boston Medical Center, particularly those with preterm births or low birth weight infants.

Probably not a fit

Patients who have pregnancies resulting from in vitro fertilization, multiple gestations, or significant fetal abnormalities may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Boston Birth Cohort Study investigates how early life exposures influence health outcomes for mothers and their children. It enrolls women delivering singleton live infants at Boston Medical Center, focusing on those with either preterm births or full-term births with low birth weight. The study collects high-quality biospecimens and comprehensive data on environmental exposures, clinical history, and maternal health through standardized interviews and medical record reviews. Follow-up assessments are conducted from birth until the child reaches 21 years of age.

Why it matters

Potential benefit: If successful, this study could provide insights into preventing adverse health outcomes related to early life exposures.

How similar studies have gone: Other studies have shown success in understanding the impact of early life factors on health, making this approach both relevant and valuable.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Mothers who deliver singleton live births at Boston Medical Center are eligible for the study.

Exclusion Criteria:

* pregnancies that are a result of in vitro fertilization or that involve multiple gestations, fetal chromosomal abnormalities or major birth defects.

Where it's running

  • Boston Medical Center
    Boston, Massachusetts, United States
    Recruiting

Study contacts

  • Principal investigator: Xiaobin Wang, MD, ScD — Johns Hopkins Bloomberg School of Public Health
  • Study coordinator: Xiaobin Wang, MD, ScD
  • Email: xwang82@jhu.edu
  • Phone: 410-9555824

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.