Study of aortic arch anatomical variations

CT Anatomical Characteristics of the Aortic Arch in Subjects With or Without Aneurysms Requiring Treatment

Observational IRCCS San Raffaele · NCT06235619

This study looks at the different shapes of the aortic arch in people with and without aneurysms to see how a common variation might relate to heart problems.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages0 Years to 100 Years
SexAll
SponsorIRCCS San Raffaele Academic / other
Locations1 site (Milan, Italy)
Trial IDNCT06235619 on ClinicalTrials.gov

What this trial studies

This observational study aims to analyze the anatomical characteristics of the aortic arch in patients with and without aneurysms using CT scans across five major cardiovascular centers in Europe. It focuses on the prevalence of a common anatomical variant known as the common origin of the innominate and left carotid artery (CILCA) and its potential association with thoracic aortic disease. By gathering and reporting detailed CT data, the study seeks to enhance understanding of this variant's implications for patient management and treatment.

Who should consider this trial

Good fit: Ideal candidates for this study are patients who have undergone aortic arch CT scans at the participating centers.

Not a fit: Patients without any aortic arch CT scans or those not meeting the inclusion criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the identification and management of patients at risk for thoracic aortic disease.

How similar studies have performed: While this study focuses on a specific anatomical variant, similar studies have shown that understanding anatomical variations can lead to better patient outcomes in thoracic aortic diseases.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

all patients with aortic arch CT scan at investigating centers

Exclusion Criteria:

none

Where this trial is running

Milan, Italy

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aortic ArchAneurysmDissection, AorticAortic archBovine archThoracic aortic disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.