Study of a new radiotracer for cancer imaging
Official title: 68Ga-JH12 PET/CT: Dosimetry and Biodistribution Study in Patients With Various Cancers
Run by First Affiliated Hospital of Fujian Medical University · NCT06688188 · Data updated 2026-11-12
This study is testing a new imaging agent for cancer to see how well it helps doctors spot tumors in patients with different types of cancer.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 5 (estimated) |
| Sponsor | First Affiliated Hospital of Fujian Medical University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Fuzhou, Fujian) |
| Status | Recruiting |
| Started | November 1, 2024 |
| Main results expected | June 30, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | November 14, 2024 |
| Trial ID | NCT06688188 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with various solid tumors who have confirmed histopathological findings.
✕Probably not a fit
Patients who are pregnant, lactating, or have severe hepatic and renal insufficiency may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the safety, biodistribution, and radiation dosimetry of a novel radiotracer, 68Ga-JH12, which targets the C-X-C motif chemokine receptor 4 (CXCR4) in patients with various types of cancer. The research aims to determine how well this radiopharmaceutical accumulates in tumors and its potential effectiveness in imaging malignant neoplasms. By analyzing the dosimetric characteristics of 68Ga-JH12, the study seeks to enhance cancer diagnosis and treatment planning. Participants will undergo PET/CT scans to assess the radiotracer's performance in real-time.
Why it matters
Potential benefit: If successful, this study could improve cancer imaging techniques, leading to better diagnosis and treatment strategies for patients with malignant tumors.
How similar studies have gone: Other studies have shown success with similar approaches targeting CXCR4 in cancer imaging, indicating a promising avenue for further exploration.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Various solid tumors with available histopathological findings * Signed informed consent Exclusion Criteria: * pregnant or lactational women * who suffered from severe hepatic and renal insufficiency
Where it's running
-
Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, China Recruiting
Study contacts
- Study coordinator: Weibing Miao, MD
- Email: miaoweibing@126.com
- Phone: +86-0591-87981618
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.