Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 18 to 80

Study of a new radiotracer for cancer imaging

Official title: 68Ga-JH12 PET/CT: Dosimetry and Biodistribution Study in Patients With Various Cancers

Run by First Affiliated Hospital of Fujian Medical University · NCT06688188 · Data updated 2026-11-12

This study is testing a new imaging agent for cancer to see how well it helps doctors spot tumors in patients with different types of cancer.

More Malignant Neoplasm trials

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment5 (estimated)
SponsorFirst Affiliated Hospital of Fujian Medical University
Academic / other
Drugs / interventionsradiation
Locations1 site (Fuzhou, Fujian)
StatusRecruiting
StartedNovember 1, 2024
Main results expectedJune 30, 2025
Study endsDecember 31, 2025
Registry record updatedNovember 14, 2024
Trial IDNCT06688188 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with various solid tumors who have confirmed histopathological findings.

Probably not a fit

Patients who are pregnant, lactating, or have severe hepatic and renal insufficiency may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the safety, biodistribution, and radiation dosimetry of a novel radiotracer, 68Ga-JH12, which targets the C-X-C motif chemokine receptor 4 (CXCR4) in patients with various types of cancer. The research aims to determine how well this radiopharmaceutical accumulates in tumors and its potential effectiveness in imaging malignant neoplasms. By analyzing the dosimetric characteristics of 68Ga-JH12, the study seeks to enhance cancer diagnosis and treatment planning. Participants will undergo PET/CT scans to assess the radiotracer's performance in real-time.

Why it matters

Potential benefit: If successful, this study could improve cancer imaging techniques, leading to better diagnosis and treatment strategies for patients with malignant tumors.

How similar studies have gone: Other studies have shown success with similar approaches targeting CXCR4 in cancer imaging, indicating a promising avenue for further exploration.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Various solid tumors with available histopathological findings
* Signed informed consent

Exclusion Criteria:

* pregnant or lactational women
* who suffered from severe hepatic and renal insufficiency

Where it's running

  • Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University
    Fuzhou, Fujian, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.