Clinical trial Recruiting at 1 site Interventional Ages 18 to 100

Stress and cardiac arrest: measuring cortisol in hair

Official title: Stress as a Key Factor Influencing the Onset and Course of Cardiac Arrest

Run by University Hospital Pilsen · NCT07285915 · Data updated 2026-11-12

This project will test whether a small hair sample can show long-term cortisol (stress) levels in adults who had an out-of-hospital cardiac arrest.

More Cardiac Arrest (CA) trials

Quick facts

Study typeInterventional
Ages18 Years to 100 Years
SexAll
Enrollment136 (estimated)
SponsorUniversity Hospital Pilsen
Academic / other
Locations1 site (Pilsen, Czech Republic)
StatusRecruiting
StartedJanuary 8, 2026
Main results expectedJuly 31, 2027
Study endsOctober 31, 2027
Registry record updatedMay 1, 2026
Trial IDNCT07285915 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–100 who experienced a cardiac arrest and can provide a small hair sample, and who are not on chronic corticosteroid or antidepressant treatment and whose participation is not refused by relatives, are ideal candidates.

Probably not a fit

Patients on long-term corticosteroids or antidepressants, those without sufficient hair, or cases where relatives withhold consent are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will collect a 3 cm hair sample from adult survivors of out-of-hospital cardiac arrest to measure cortisol levels that reflect roughly the prior three months of stress exposure. Hair cortisol results will be compared with anonymized clinical records, including details of prehospital care and post-resuscitation condition. The study seeks links between chronic stress markers and patient characteristics, severity of post-resuscitation syndrome, and outcomes. By focusing specifically on out-of-hospital cardiac arrest, the project addresses a gap in existing data about stress as a contributing factor.

Why it matters

Potential benefit: If successful, this approach could identify patients with high chronic stress after cardiac arrest and inform targeted support or prevention strategies.

How similar studies have gone: Hair cortisol has been used to measure chronic stress in other cardiovascular research, but applying it specifically to out-of-hospital cardiac arrest is relatively novel and data are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Cardiac arrest
* Heart attack
* 18 - 100 years

Exclusion Criteria:

* Disapproval patient´s relatives with the study
* Chronical treatment with corticoids and antidepresives

Where it's running

  • University Hospital Pilsen
    Pilsen, Czech Republic, Czechia
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.