Strength training to reduce late effects in young cancer survivors
Strength Training Exercises to Minimise Late Effects of Childhood Leukaemia or Lymphoma Among Adolescents - The STEEL Study - a National Multicenter Randomised Controlled Study
This study is testing if a 16-week strength training program can help young cancer survivors feel stronger and improve their quality of life compared to a different exercise program.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 10 Years to 19 Years |
| Sex | All |
| Sponsor | Aalborg University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 4 sites (Copenhagen and 3 other locations) |
| Trial ID | NCT06299722 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to include 60 children and adolescents aged 10 to 19 who have successfully completed treatment for leukemia or lymphoma. Participants will be randomly assigned to either a 16-week strength training program (STEEL) or a circuit training program, both designed to improve muscle strength and overall quality of life. The training will take place in local centers, and participants will receive guidance on late effects of treatment, diet, sleep, and exercise. The study will evaluate the effectiveness of these training modalities through self-reported quality of life and physical assessments at baseline, 8 weeks, and 16 weeks.
Who should consider this trial
Good fit: Ideal candidates are children and adolescents aged 10 to 19 who have completed chemotherapy for leukemia or lymphoma at least 12 months prior.
Not a fit: Patients currently participating in similar research studies or those with contraindications to exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the quality of life and physical health of young cancer survivors by mitigating late effects of their treatment.
How similar studies have performed: Other studies have shown positive outcomes with exercise interventions for cancer survivors, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ten to 19 years of age at the point of inclusion * A minimum of 12 months since the last chemotherapy with no upper limit * Ability to understand the physical intervention and general participant advice Exclusion Criteria: * Participation in another research study that includes similar treatment * Pregnancy * Cardiac arrhythmia during exercise * Psychological disorders interfering with treatment * Presence of a clinical condition that needs immediate treatment * Planned surgeries within the subsequent 12 months that may interfere with performing exercises * Any contraindications to performing physical exercise as evaluated by the recruiting medical doctor
Where this trial is running
Copenhagen and 3 other locations
- Rigshospitalet — Copenhagen, Denmark (Recruiting)
- Aalborg University — Gistrup, Denmark (Recruiting)
- Odense University Hospital — Odense, Denmark (Recruiting)
- Århus University Hospital — Århus, Denmark (Recruiting)
Study contacts
- Study coordinator: Henrik Riel, PhD
- Email: hriel@dcm.aau.dk
- Phone: +4530201570
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.