Stratified treatment for pediatric rhabdomyosarcoma based on risk factors
Official title: A Prospective Clinical Cohort Study on Stratified Treatment of Rhabdomyosarcoma Based on Risk Factors: a Single Arm Trial.
Run by Sun Yat-sen University · NCT06836492 · Data updated 2026-11-12
This study is testing a new treatment plan for children with rhabdomyosarcoma to see if combining chemotherapy and radiotherapy helps improve survival based on their risk levels.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 0 Years to 18 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Sun Yat-sen University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | January 30, 2017 |
| Main results expected | September 2029 |
| Study ends | December 2029 |
| Registry record updated | February 20, 2025 |
| Trial ID | NCT06836492 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are children aged 0 to 18 years who have been newly diagnosed with rhabdomyosarcoma.
✕Probably not a fit
Patients with immunodeficiency diseases or those who have a second tumor may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to evaluate the efficacy and safety of the SYSUCC-RMS treatment regimen for children diagnosed with rhabdomyosarcoma (RMS). It will assess the impact of combining chemotherapy and radiotherapy on survival rates across different risk categories: low, medium, high, and extremely high risk. The study will include pediatric patients aged 0 to 18 years who are receiving treatment for the first time and will monitor their outcomes based on their specific risk factors.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for children with rhabdomyosarcoma, improving survival rates.
How similar studies have gone: Other studies have shown promise in stratified treatment approaches for pediatric cancers, suggesting potential success for this methodology.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. 0 years \< age \< 18 years old, regardless of gender; 2. Tumor patients diagnosed by histopathology or bone marrow cytology; 3. Patients are treated for the first time; 4. ECoG score ≤ 2; 5. The expected survival time is more than 8 months; 6. Patient's parent or guardian signs informed consent. Exclusion Criteria: 1. Combined with immunodeficiency disease 2. Second tumor
Where it's running
-
Suying Lu
Guangzhou, Guangdong, China Recruiting
Study contacts
- Study coordinator: Suying Lu
- Email: lusy@sysucc.org.cn
- Phone: +020-87342460
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.