Stratified-care school program for teens with suicidal thoughts

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-arm, quasi-experimental project delivering a culturally adapted stratified-care model in six secondary schools in Santiago, Chile, with pre-post measurements and follow-ups at 3, 6, 9, and 12 months. Students with recent suicidal ideation are screened with the C-SSRS and PHQ-9 and are routed to Reframe-IT+ if their PHQ-9 is below 20 or to CARIBOU if their PHQ-9 is 20 or higher. Both interventions are individually delivered, CBT-based programs adapted for the local context and aimed at reducing depressive symptoms and suicidal ideation. The study focuses on schools with high socioeconomic vulnerability and collects outcome data over one year to measure change.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Inclusion Criteria for Educational Institutions

  * Located in Santiago, Chile.
  * Secondary education level (grades I-IV Medio).
  * Coeducational schools.
  * At least two classes per grade level in secondary education.
  * A minimum of 30 students per class.
  * Socioeconomic vulnerability level of ≥ 50%, as measured by the School Vulnerability Index (Índice de Vulnerabilidad Escolar - IVE-SINAE), which includes factors such as parental education and total household income.

Inclusion Criteria for Students

* Enrolled in grades I, II, or III Medio.
* Suicidal ideation within the past month, defined as a score ≥ 3 on the Columbia-Suicide Severity Rating Scale (C-SSRS).
* For the Reframe-IT+ program: mild or moderate depressive symptoms, defined as a PHQ-9 score \< 20.
* For the CARIBOU program: severe depressive symptoms, defined as a PHQ-9 score ≥ 20.

Exclusion Criteria:

* Exclusion Criteria for Students

  * Participation in a structured suicide prevention program (Reframe-IT+) during 2024.
  * Severe psychotic symptoms, such as perceptual disturbances or delusional ideas, assessed during the eligibility interview.
  * Suicide attempt(s) in the past three months, assessed during the eligibility interview.

Where it's running

• Universidad de los Andes
  Santiago, Las Condes, Chile Recruiting

Study contacts

• Study coordinator: Jorge E Gaete, MD, PhD
• Email: jgaete@uandes.cl
• Phone: +56940245650

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.