Strategies to manage weight through environmental and impulse control

Evaluating Environmental Control (AVOID) and Inhibitory Control (RESIST) Strategies to Improve Weight Management Outcomes

Not applicable Interventional Cedars-Sinai Medical Center · NCT05143931

This study is testing different ways to help people with overweight or obesity lose weight and improve their diets over a year by trying out standard methods, changes to their environment, impulse control training, or a mix of both.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment503 (estimated)
Ages14 Years and up
SexAll
SponsorCedars-Sinai Medical Center Academic / other
Locations1 site (Los Angeles, California)
Trial IDNCT05143931 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates two self-regulatory approaches aimed at improving weight loss and diet quality in individuals with overweight or obesity. Participants will be enrolled in a 12-month weight management program and randomly assigned to one of four groups: standard program, program with environmental modifications, program with impulse control training, or a combination of both strategies. The study will assess the effectiveness of these interventions on weight loss and diet quality over 6 and 12 months. A total of 500 participants will be recruited from the Cedars-Sinai Medical Center network.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with a BMI between 25-45 kg/m2 who can read, write, and speak English.

Not a fit: Patients currently enrolled in weight loss interventions, pregnant women, or those with contraindications to weight loss may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide innovative strategies for effective weight management and improved diet quality for individuals struggling with obesity.

How similar studies have performed: Previous studies have shown promise in using behavioral strategies for weight management, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria (Main participants):

* Age 18 years or older
* BMI between 25-45 kg/m2
* Read, write, and speak English with acceptable visual acuity
* Has a household member (≥ 14 years) willing to complete three brief assessments over 12 months\* \*Only applies to individuals who indicate they are cohabitating with at least one eligible household member

Inclusion Criteria (Household participants):

* 14-years-old
* Parent consent for children \<18-years-old
* Willingness to complete assessments / measurements

Exclusion Criteria (Main participants):

* Currently enrolled in weight loss interventions or undergoing bariatric surgery
* Pregnant women
* Individuals for whom weight loss may be contraindicated (e.g., unstable coronary artery disease, end-stage disease, active cancer treatment, uncontrolled insulin-dependent diabetes, portal hypertension, drug/alcohol abuse)
* Individuals with severe cognitive delays or visual/hearing impairment
* Individuals who are unable or unwilling to complete the study assessments / measurements

Exclusion Criteria (Household participants):

* ≤ 14-years-old
* Individuals who are unable or unwilling to complete the study assessments / measurements

Where this trial is running

Los Angeles, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ObesityOverweight
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.