Step training for older adults with mild dementia
Official title: Investigating the Effects of Step Training and the Mediating Effects of Prefrontal Cortex Functioning in Older Adults with Mild Dementia: a Randomized Wait-list Controlled Trial
Run by The Hong Kong Polytechnic University · NCT05655403 · Data updated 2026-11-12
This study tests if a step-training program can help older adults with mild dementia improve their balance and reduce their risk of falling.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 145 (estimated) |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | January 1, 2024 |
| Main results expected | September 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | March 13, 2025 |
| Trial ID | NCT05655403 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 65 and older with a physician's diagnosis of mild dementia and the ability to walk independently.
✕Probably not a fit
Patients with severe musculoskeletal, cardiorespiratory, or neurological conditions, or those with significant sensory impairments may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project investigates the effects of a step-training program on older adults with mild dementia, focusing on improving choice stepping and reducing fall-related outcomes. The training involves concurrent stepping and visuospatial tasks to enhance cognitive and motor functions. The study aims to assess changes in step length, lower-limb muscle strength, balance, mobility, dual-task ability, and fear of falling. By understanding the impact of step training on the prefrontal cortex, the research seeks to provide insights into fall prevention strategies for this vulnerable population.
Why it matters
Potential benefit: If successful, this study could significantly reduce the risk of falls in older adults with mild dementia, enhancing their safety and quality of life.
How similar studies have gone: While step training has shown effectiveness in healthy older adults, this specific application in older adults with mild dementia is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * at least 65 years old; * have a physician's diagnosis of dementia according to the Diagnostic and Statistical Manual of Mental Disorders 5th edition; * have mild dementia, indicated by a score of 10 or higher on the Montreal Cognitive Assessment Hong Kong version (HK-MoCA); * able to walk 10 meters independently without a walking aid; * receiving care by an unpaid "main caregiver" with at least 3.5 hours of face-to-face contact per week. Exclusion Criteria: * unable to perform step training due to unstable or severe musculoskeletal, cardiorespiratory, or neurological conditions; * have severe hearing and/or visual impairments that limit their ability to communicate; * have been hospitalized within the past 30 days.
Where it's running
-
The Hong Kong Polytechnic University
Hong Kong, Hong Kong Recruiting
Study contacts
- Principal investigator: Wayne LS Chan, PhD — The Hong Kong Polytechnic University
- Study coordinator: Wayne LS Chan, PhD
- Email: wayne.ls.chan@polyu.edu.hk
- Phone: +852 27666742
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Diabetes, Dementia, and Oxidative Stress: A look at Nox2-related markers
This study tests whether oxidative stress linked to Nox2 is related to dementia risk in adults with type 2 diabetes.
-
China HEAD: a large community study on healthy aging and dementia
This study tests whether collecting health, imaging, and biospecimen data from adults in China can help predict who will develop Alzheimer’s disease and related dementias.
-
Doll Therapy for Apathy and Daily Living in Older Adults with Dementia
This study tests whether doll therapy helps reduce apathy and improves starting daily activities in older adults with dementia.
-
Aging Brain Health Initiative in Fujian
This observational study will follow about 3,000 older adults in Fujian to see how Alzheimer's-related changes develop and to test new digital tests, biomarkers, and imaging tools for early diagnosis.
-
One-day exercise test to see how brain and body react in epilepsy, cognitive disorders, Parkinson's, dementia, and related conditions
A one-day study tests how an acute bout of exercise changes brain function and bodily signals in people with certain neurological conditions compared with healthy individuals.
-
Blood biomarker cohort for memory disorders in older adults
This observational cohort will collect blood samples and brain imaging data from adults 50+ with memory disorders and a small group of healthy young adults to help find biomarkers.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.