Stent-assisted Coil Embolization for Acute Ruptured Intracranial Aneurysms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates the perioperative safety and effectiveness of stent-assisted coil embolization for acute ruptured intracranial aneurysms. Patients receive a stent and coils, with postoperative intravenous antiplatelet therapy guided by a predefined protocol. Primary endpoints include perioperative complications, new ischemic or bleeding events within 30 days, and perioperative mortality. Secondary endpoints assess immediate embolization grade, 30-day functional status, and long-term aneurysm occlusion and restenosis up to one year. The trial aims to determine if this approach provides a safe and effective option for patients requiring urgent interventional treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 18-80 with a single ruptured cystic aneurysm at the center, or multiple aneurysms with a clear responsible lesion, only treat the responsible lesion
* Aneurysms with a wide neck, neck ≥4mm, or neck/body ratio \>1/2
* Treatment performed within 7 days of the last hemorrhage
* Patients undergoing interventional treatment using a stent, including cases of remedial stent use.5. Hunt \& Hess grade 1-3

Exclusion Criteria:

* Exclude patients who meet the inclusion criteria but fail to undergo successful SAC embolization
* Exclude non-cystic aneurysms, such as dissection, pseudoaneurysm, and distal aneurysm patients
* Patients with other cerebrovascular diseases, including AVM, DAVF, Moyamoya disease, and arterial stenosis greater than 50%
* Patients unable to use intravenous antiplatelet drugs
* Patients with poor condition prior to aneurysm rupture, mRS ≥ 2
* Exclude pregnant patients
* Exclude patients with other severe preoperative diseases, such as malignant tumors or cardiopulmonary and renal diseases
* Patients with multiple aneurysms where the responsible lesion cannot be identified and treatment is done for all

Where it's running

• Tangdu Hospital,Fourth Military Medical University,Xi'an,Shaanxi 710038
  Xi'an, Shaanxi, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.