St. John's Wort oil for cesarean scar healing and pain
Official title: The Effect of St. John's Wort Oil on Wound Healing and Pain in Women Undergoing Cesarean Section: A Randomized Controlled Trial
Run by Sakarya University · NCT07012278 · Data updated 2026-11-12
This test tries applying St. John's Wort (Hypericum perforatum) oil to the cesarean scar to see if it speeds healing and reduces pain for women after their first C-section.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 80 (estimated) |
| Sponsor | Sakarya University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Sakarya) |
| Status | Recruiting |
| Started | June 25, 2025 |
| Main results expected | December 30, 2025 |
| Study ends | April 30, 2026 |
| Registry record updated | June 10, 2025 |
| Trial ID | NCT07012278 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women who have had their first cesarean delivery, are fluent in Turkish, and are willing to receive topical treatment and attend follow-up at Sakarya University.
✕Probably not a fit
Women with complex wound infections requiring systemic antibiotics or surgery, those who do not speak Turkish, or those who decline participation are unlikely to benefit from this topical intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Women who have had their first cesarean section and speak Turkish will receive topical applications of St. John's Wort oil to the cesarean scar as a dressing. The study will track wound healing and pain using clinical wound checks and patient-reported pain measures over the postpartum follow-up period. The protocol focuses on a herbal, topical approach as an alternative to standard pharmacologic wound care and excludes those who decline or cannot communicate in Turkish. All treatment and follow-up take place at the Sakarya University site.
Why it matters
Potential benefit: If effective, the oil could provide a low-cost, well-tolerated topical option to speed scar healing and reduce pain after cesarean delivery.
How similar studies have gone: Some preclinical work and small clinical reports suggest topical St. John's Wort may aid wound healing and pain, but high-quality randomized evidence for cesarean scars is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Volunteering to participate in the research, * Having had a cesarean section, * Her first cesarean section, * Being fluent in Turkish. Exclusion Criteria: * Not wanting to participate in the research, * The existence of a communication barrier.
Where it's running
-
Sakarya Üniversity
Sakarya, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Bilge Nur Yıldırım Bayraktar Dr., PhD
- Email: bilgeyildirim41@gmail.com
- Phone: 507-421-25-70
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.