St. John's Wort oil for cesarean scar healing and pain
The Effect of St. John's Wort Oil on Wound Healing and Pain in Women Undergoing Cesarean Section: A Randomized Controlled Trial
This test tries applying St. John's Wort (Hypericum perforatum) oil to the cesarean scar to see if it speeds healing and reduces pain for women after their first C-section.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Sakarya University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Sakarya) |
| Trial ID | NCT07012278 on ClinicalTrials.gov |
What this trial studies
Women who have had their first cesarean section and speak Turkish will receive topical applications of St. John's Wort oil to the cesarean scar as a dressing. The study will track wound healing and pain using clinical wound checks and patient-reported pain measures over the postpartum follow-up period. The protocol focuses on a herbal, topical approach as an alternative to standard pharmacologic wound care and excludes those who decline or cannot communicate in Turkish. All treatment and follow-up take place at the Sakarya University site.
Who should consider this trial
Good fit: Women who have had their first cesarean delivery, are fluent in Turkish, and are willing to receive topical treatment and attend follow-up at Sakarya University.
Not a fit: Women with complex wound infections requiring systemic antibiotics or surgery, those who do not speak Turkish, or those who decline participation are unlikely to benefit from this topical intervention.
Why it matters
Potential benefit: If effective, the oil could provide a low-cost, well-tolerated topical option to speed scar healing and reduce pain after cesarean delivery.
How similar studies have performed: Some preclinical work and small clinical reports suggest topical St. John's Wort may aid wound healing and pain, but high-quality randomized evidence for cesarean scars is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Volunteering to participate in the research, * Having had a cesarean section, * Her first cesarean section, * Being fluent in Turkish. Exclusion Criteria: * Not wanting to participate in the research, * The existence of a communication barrier.
Where this trial is running
Sakarya
- Sakarya Üniversity — Sakarya, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Bilge Nur Yıldırım Bayraktar Dr., PhD
- Email: bilgeyildirim41@gmail.com
- Phone: 507-421-25-70
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.