Clinical trial Recruiting at 1 site Interventional Ages 18 to 45 Women only

St. John's Wort oil for cesarean scar healing and pain

Official title: The Effect of St. John's Wort Oil on Wound Healing and Pain in Women Undergoing Cesarean Section: A Randomized Controlled Trial

Run by Sakarya University · NCT07012278 · Data updated 2026-11-12

This test tries applying St. John's Wort (Hypericum perforatum) oil to the cesarean scar to see if it speeds healing and reduces pain for women after their first C-section.

More Wound Healing trials

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexWomen only
Enrollment80 (estimated)
SponsorSakarya University
Academic / other
Drugs / interventionsradiation
Locations1 site (Sakarya)
StatusRecruiting
StartedJune 25, 2025
Main results expectedDecember 30, 2025
Study endsApril 30, 2026
Registry record updatedJune 10, 2025
Trial IDNCT07012278 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women who have had their first cesarean delivery, are fluent in Turkish, and are willing to receive topical treatment and attend follow-up at Sakarya University.

Probably not a fit

Women with complex wound infections requiring systemic antibiotics or surgery, those who do not speak Turkish, or those who decline participation are unlikely to benefit from this topical intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Women who have had their first cesarean section and speak Turkish will receive topical applications of St. John's Wort oil to the cesarean scar as a dressing. The study will track wound healing and pain using clinical wound checks and patient-reported pain measures over the postpartum follow-up period. The protocol focuses on a herbal, topical approach as an alternative to standard pharmacologic wound care and excludes those who decline or cannot communicate in Turkish. All treatment and follow-up take place at the Sakarya University site.

Why it matters

Potential benefit: If effective, the oil could provide a low-cost, well-tolerated topical option to speed scar healing and reduce pain after cesarean delivery.

How similar studies have gone: Some preclinical work and small clinical reports suggest topical St. John's Wort may aid wound healing and pain, but high-quality randomized evidence for cesarean scars is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Volunteering to participate in the research,
* Having had a cesarean section,
* Her first cesarean section,
* Being fluent in Turkish.

Exclusion Criteria:

* Not wanting to participate in the research,
* The existence of a communication barrier.

Where it's running

  • Sakarya Üniversity
    Sakarya, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.