Spinal vs. General Anesthesia for Open Simple Prostatectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective randomized study compares two anesthesia approaches for open simple prostatectomy in men with BPH. Participants are randomized to receive either spinal or general anesthesia, with no tranexamic acid or additional hemostatic agents used perioperatively. Postoperative bleeding outcomes will be tracked through changes in hemoglobin and hematocrit, transfusion needs, presence of hematuria, clot retention, bladder irrigation requirements, and any bleeding-related reinterventions. The goal is to see if spinal anesthesia offers better bleeding control and recovery compared with general anesthesia. Safety and feasibility in an adult surgical population will also be observed.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male patients aged 18 years or older.
* Diagnosis of benign prostatic hyperplasia (BPH).
* Scheduled to undergo open simple prostatectomy.
* American Society of Anesthesiologists (ASA) physical status I-III.
* Ability to provide written informed consent.

Exclusion Criteria:

* Refusal or inability to provide informed consent.
* Patients scheduled for radical prostatectomy due to prostate cancer.
* Emergency surgery.
* Known coagulation disorders or clinically significant thrombocytopenia.
* Ongoing anticoagulant or antiplatelet therapy that cannot be discontinued according to institutional protocols.
* Contraindication to spinal anesthesia.
* Participation in another interventional clinical trial that may affect study outcomes.
* Administration of tranexamic acid or any additional hemostatic agent during the perioperative period.

Where it's running

• Hitit university
  Çorum, Turkey (Türkiye) Recruiting
• hitit Üniversity
  Çorum, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Mustafa Serdar Çağlayan
• Email: serdar.09.09@hotmail.com
• Phone: +905074311951

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.