Spinal Cord-Targeted Stimulation to Improve Hand Function in Hemiplegic Cerebral Palsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial explores a non-invasive approach called spinal cord associative plasticity, combining stimulation of the hand motor cortex and the median nerve to induce plastic changes in the cervical spinal cord. Researchers will verify stimulation parameters that may promote sensorimotor plasticity and measure neurophysiological, biomechanical, and functional outcomes related to hand dexterity. If initial findings show meaningful improvements, results could justify a larger study to confirm benefits for upper limb movement. The study uses Paired brain and nerve stimulation with careful attention to safety and tolerability in adults with hCP.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Maintenance of caffeine and exercise levels at time of sessions
* Ability to provide informed consent
* Manual ability classification system (MACS) level I to III

Exclusion Criteria:

* History of seizures in last two years
* Use of medications that lower seizure threshold
* History of implanted equipment including stimulators/pacemakers

Where it's running

• Columbia University Irving Medical Center
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Jason Carmel, MD, PhD — Columbia University
• Study coordinator: Shaker Dukkipati, MD, PhD
• Email: sd3850@cumc.columbia.edu
• Phone: 2123046501

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.