Speech treatment for minimally verbal children with autism and speech disorders
Official title: Speech Treatment for Minimally Verbal Children With ASD and CAS
Run by MGH Institute of Health Professions · NCT05066178 · Data updated 2026-11-12
This study is testing if a special speech treatment can help minimally verbal children with autism speak more clearly by using fun activities and targeted practice.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 5 Years to 18 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | MGH Institute of Health Professions Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | May 1, 2024 |
| Main results expected | April 30, 2030 |
| Study ends | November 30, 2030 |
| Registry record updated | March 30, 2026 |
| Trial ID | NCT05066178 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are minimally verbal children diagnosed with both Autism Spectrum Disorder and Childhood Apraxia of Speech who can repeat at least two syllables.
✕Probably not a fit
Patients with poorly controlled seizures, additional sensory impairments, or significant behavioral challenges may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the impact of Childhood Apraxia of Speech (CAS) on speech development in minimally verbal children with Autism Spectrum Disorder (ASD). It aims to determine if CAS-specific treatment can improve speech intelligibility in these children. The approach involves identifying a cohort of 20 children and providing them with 15 one-hour treatment sessions that incorporate play-based activities and motor learning principles. The treatment focuses on practicing specific words that align with each child's speech challenges, using various supportive cues to enhance their speech production.
Why it matters
Potential benefit: If successful, this treatment could significantly improve speech intelligibility in minimally verbal children with autism, enhancing their communication skills.
How similar studies have gone: While this approach is novel in its specific focus on CAS in minimally verbal children with autism, similar interventions for speech disorders have shown promise in other populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Meets criteria for Autism Spectrum Disorder * Able to correctly repeat at least 2 syllables * Meets criteria for Childhood Apraxia of Speech * Lives in an environment where child is exposed to English at least 50% of the time Exclusion Criteria: * Poorly controlled seizures * Factors such as blindness or deafness that contribute to minimally verbal status * Lives in an environment where English is not spoken at least 50% of the time * Child experiences behavioral challenges that preclude participation in the study
Where it's running
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MGH Institute of Health Professions
Boston, Massachusetts, United States Recruiting
Study contacts
- Study coordinator: Karen V Chenausky, Ph.D.
- Email: kvchenausky@mghihp.edu
- Phone: 617-726-2405
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.