Speech assessment in patients with Parkinson's disease and impulse control issues
Official title: STIMPulseControl Ancillary Speech Study
Run by University of Kiel · NCT06561919 · Data updated 2026-11-12
This study tests how deep brain stimulation for impulse control in Parkinson's disease affects patients' speech over time.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of Kiel Academic / other |
| Locations | 13 sites (Cologne and 12 other locations) |
| Status | Recruiting |
| Started | September 5, 2024 |
| Main results expected | July 15, 2027 |
| Study ends | July 15, 2028 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT06561919 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with Parkinson's disease who are participating in the main STIMPulseControl study and are undergoing deep brain stimulation.
✕Probably not a fit
Patients who do not have Parkinson's disease or those not participating in the main STIMPulseControl study may not benefit from this ancillary study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This ancillary study focuses on analyzing the speech of patients enrolled in the main STIMPulseControl study, which investigates the effects of deep brain stimulation on impulse control in Parkinson's disease. Speech recordings will be taken at three time points: before surgery, and at 6 and 12 months post-surgery. The recordings will follow a standardized protocol and will be analyzed for various speech features to assess the impact of surgical and pharmacological interventions on speech and cognitive outcomes. The goal is to understand how these interventions affect motor and emotional aspects of speech in patients with Parkinson's disease.
Why it matters
Potential benefit: If successful, this study could provide insights into the relationship between speech features and cognitive changes in Parkinson's disease, potentially improving treatment strategies.
How similar studies have gone: While this specific approach is part of a larger study, similar studies have shown promise in understanding speech changes in Parkinson's disease, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Please refer to main study (STIMPulseControl KKS-313) Exclusion Criteria: Please refer to main study (STIMPulseControl KKS-313)
Where it's running
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University Hospital Cologne
Cologne, Germany Recruiting -
University Hospital Carl Gustav Carus
Dresden, Germany Recruiting -
University Hospital Duesseldorf
Düsseldorf, Germany Recruiting -
University Medical Center Hamburg-Eppendorf
Hamburg, Germany Recruiting -
University Hospital Schleswig-Holstein (UKSH), Campus Kiel
Kiel, Germany Recruiting -
University Hospital of Giessen and Marburg (UKGM), Campus Marburg
Marburg, Germany Recruiting
Show 7 more locations
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Charité Campus Mitte
Mitte, Germany Recruiting -
University Hospital Tuebingen
Tübingen, Germany Recruiting -
University Hospital Wuerzburg
Würzburg, Germany Recruiting -
Amsterdam University Medical Center
Amsterdam, Netherlands Recruiting -
University Hospital of Bern (Inselspital)
Bern, Switzerland Recruiting -
University Hospital Zuerich (USZ)
Zurich, Switzerland Recruiting -
Paracelsus - Elena- Klinik
Kassel, Germany Not yet recruiting
Study contacts
- Study coordinator: Steffen Paschen, MD
- Email: steffen.paschen@uksh.de
- Phone: 0049 431 500 23819
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Prediction-model guided drug choice to prevent impulse control disorders in Parkinson's
This trial tests whether an algorithm-guided approach to prescribing Parkinson’s disease medicines can reduce impulse control problems compared with usual care in adults with Parkinson’s.
-
Understanding impulsivity in Parkinson's patients with deep brain stimulation
This study is testing how deep brain stimulation affects impulsivity in people with Parkinson's disease to see if different settings can help reduce impulsive behavior.
-
Using rTMS to treat impulse control disorders in Parkinson's disease
This study is testing if a treatment called rTMS can help people with Parkinson's disease who struggle with impulse control issues feel more in control of their behaviors.
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A one-day study tests how an acute bout of exercise changes brain function and bodily signals in people with certain neurological conditions compared with healthy individuals.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.