Clinical trial Recruiting at 1 site Observational Ages 18 to 25

Smoking's effect on lower-limb speed and coordination in young adults.

Official title: Investigation of the Impact of Smoking Addiction on the Speed and Coordination of Lower Extremity Movements

Run by Saglik Bilimleri Universitesi · NCT07061522 · Data updated 2026-11-12

We will test whether young adults who smoke have slower or less coordinated leg movements compared with non-smokers.

Quick facts

Study typeObservational
Ages18 Years to 25 Years
SexAll
Enrollment24 (estimated)
SponsorSaglik Bilimleri Universitesi
Academic / other
Locations1 site (Istanbul, Üsküdar)
StatusRecruiting
StartedAugust 26, 2025
Main results expectedJuly 20, 2026
Study endsJuly 20, 2026
Registry record updatedAugust 27, 2025
Trial IDNCT07061522 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are literate, cooperative adults aged 18–25 with BMI 18.5–29.9 who either smoke at least one cigarette daily for 12 months or more or are non-smokers for comparison.

Probably not a fit

People with orthopedic, neurological, or neuromuscular conditions, chronic pulmonary or cardiac disease, cognitive impairment, or BMI ≥30 are excluded and unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational case-control study compares motor coordination and sprint speed between smokers and non-smokers aged 18–25. Participants are classified using DSM-IV-TR nicotine dependence criteria and the Fagerström Test and will complete the Lower Extremity Motor Coordination Test (LEMOCOT) and a 30-meter sprint under standardized laboratory conditions. BMI and bimalleolar diameter and circumference will be recorded to control for body-size confounders. Data will be analyzed to see if chronic smoking is associated with measurable deficits in lower-limb motor function.

Why it matters

Potential benefit: If smoking is linked to poorer lower-limb function, the findings could support early prevention and targeted rehabilitation to help preserve mobility in young smokers.

How similar studies have gone: Previous research links smoking to vascular and neuromuscular harm, but few controlled studies have directly measured lower-limb coordination and sprint performance, making this approach relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Smoking ≥1 cigarette daily for at least 12 months
* Age between 18-25
* Literate and cooperative
* BMI: 18.5-29.9 kg/m²

Exclusion Criteria:

* Orthopedic, neurological, or neuromuscular conditions impairing walking
* Chronic pulmonary or cardiac disease
* Cognitive impairment
* BMI ≥30 kg/m²

Where it's running

  • Esra Pehlivan
    Istanbul, Üsküdar, Turkey (Türkiye)
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.