Sleep apnea and how it affects shunts in normal-pressure hydrocephalus

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional protocol records intracranial and intra-abdominal pressures overnight in patients with normal-pressure hydrocephalus, focusing on changes during apneic episodes. The study compares pressure dynamics relevant to distal drainage into the peritoneum versus the right atrium and relates those findings to shunt patency and clinical outcomes. The protocol may include addressing obstructive sleep apnea and following patients to see whether OSA treatment changes symptoms and shunt performance. Key exclusions (cerebrovascular disease, non-NPH dementia, Parkinson's disease) are applied to reduce confounding.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical condition compatible with normal-pressure hydrocephalus

Exclusion Criteria:

* Cerebral vascular disease
* Dementia not due to normal-pressure hydrocephalus
* Parkinson's disease

Where it's running

• Vicente Vanaclocha
  Valencia, Valencia, Spain Recruiting

Study contacts

• Study coordinator: Vicente Vanaclocha
• Email: vvanaclo@hotmail.com
• Phone: 34669790013

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• White matter damage and dementia markers in normal pressure hydrocephalus

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.