Single-step treatment for maxillary sinusitis caused by dental issues
Official title: Single-step Functional Sinus Endoscopy and Transoral Surgery Enhance Odontogenic Sinusitis Treatment Outcomes: a Randomized Controlled Trial
Run by Qassim University · NCT06130176 · Data updated 2026-11-12
This study is testing a new combined treatment for people with sinus infections caused by dental problems to see if it works better than standard care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Qassim University Academic / other |
| Locations | 1 site (Buraidah, Qassim Province) |
| Status | Recruiting |
| Started | November 11, 2018 |
| Main results expected | December 1, 2026 |
| Study ends | July 1, 2027 |
| Registry record updated | June 9, 2026 |
| Trial ID | NCT06130176 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals diagnosed with odontogenic maxillary sinusitis that has not improved with standard dental or medical treatments.
✕Probably not a fit
Patients with maxillary sinus malignancy, previous sinus surgeries, or non-odontogenic sinusitis may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of a combined approach using Single-step Functional Sinus Endoscopy and Transoral Surgery for treating maxillary sinusitis resulting from odontogenic causes. It aims to address the lack of consensus among specialists regarding the optimal treatment for this specific type of sinusitis. By integrating the expertise of ENT specialists and dental/maxillofacial surgeons, the study seeks to provide a comprehensive treatment protocol. Participants will be those diagnosed with odontogenic maxillary sinusitis that has not responded to conventional dental or medical treatments.
Why it matters
Potential benefit: If successful, this approach could provide a more effective treatment option for patients suffering from odontogenic maxillary sinusitis.
How similar studies have gone: While there are various surgical techniques for treating odontogenic maxillary sinusitis, this specific integrated approach is relatively novel and has not been extensively tested in prior studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. A diagnosis of OMS that is not responding to dental treatment and/or medical treatment 2. Agreement on the odontogenic cause between an ENT specialist and a dentist/maxillofacial surgeon (There is bone loss surrounding the tooth's root and a connection between the dental lesion and sinus on CT scans) 3. Availability of clinical, radiographic, and ESS data. Exclusion Criteria: 1. Maxillary sinus malignancy 2. Sinuses with a previous surgery 3. Non-odontogenic Sinusitis
Where it's running
-
Ghada Amin Khalifa
Buraidah, Qassim Province, Saudi Arabia Recruiting
Study contacts
- Principal investigator: Ghada A Khalifa, professor — College of Dentistry, Qassim University, Saudi Arabia
- Study coordinator: Ghada A Khalifa, Professor
- Email: g.khalifa@qu.edu.sa
- Phone: 00966504840248
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.