Comparing two volumes of Articaine for dental extractions
Official title: Comparing the Effectiveness of Buccal Infiltration of Different Volumes of Articaine for Extraction of Mandibular Posterior Teeth- A Randomized Clinical Trial.
Run by Qassim University · NCT06630819 · Data updated 2026-11-12
This study is testing whether using a smaller or larger amount of a local anesthetic called Articaine helps people feel less pain during the extraction of their back teeth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 114 (estimated) |
| Sponsor | Qassim University Academic / other |
| Locations | 2 sites (Buraidah, Al Qassim and 1 other locations) |
| Status | Recruiting |
| Started | November 24, 2024 |
| Main results expected | May 2, 2026 |
| Study ends | May 2, 2026 |
| Registry record updated | May 29, 2025 |
| Trial ID | NCT06630819 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy adults aged 18 and older requiring extraction of mandibular posterior teeth.
✕Probably not a fit
Patients with acute infections at the extraction site or those requiring surgical extractions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of two different volumes of buccal infiltration of Articaine, a local anesthetic, for the extraction of mandibular posterior teeth. Participants will receive either 1.8 ml or 3.6 ml of 4% Articaine to determine which volume provides better anesthesia. The study aims to address complications associated with the inferior alveolar nerve block technique by utilizing a safer and less painful local infiltration method. The research will involve healthy patients aged 18 and older who require dental extractions.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management during dental extractions, enhancing patient comfort and outcomes.
How similar studies have gone: Previous studies have shown that local infiltration techniques can be effective, but this specific comparison of Articaine volumes is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All healthy patients (ASA I) or patients with mild systemic disease with no functional limitations (ASA II) * Patients aged ≥ 18 years of age. * Patients requiring extraction of mandibular posterior teeth including grossly decayed tooth, grade I mobile tooth, root stumps and indicated for therapeutic reasons. * Patients not allergic to the drugs or anesthetic agents used in the surgery. Exclusion Criteria: * Acute infection at the extraction site. * Patients indicated for surgical extraction of teeth. * Patients already taking medications affecting pain assessment. * Pregnant patients.
Where it's running
-
College of Dentistry, Qassim University
Buraidah, Saudi Arabia Recruiting -
Qassim University
Buraidah, Al Qassim, Saudi Arabia Not yet recruiting
Study contacts
- Study coordinator: Muhammad Atif S Agwan
- Email: m.abdulsaleem@qu.edu.sa
- Phone: 966541651713
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.