Short-term personalized nutrition plus health education after colorectal cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, open-label, multicenter trial that will enroll about 360 patients who have had surgery for non-metastatic colorectal cancer and are at nutritional risk. Participants are randomly assigned to one of four groups: personalized nutritional support plus structured health education, health education alone, nutritional support alone, or standard care. Nutritional support includes individualized diet counseling and oral (or parenteral when needed) supplements, while health education is delivered via a digital platform with weekly videos and interactive content. The intervention lasts 14 days with clinical and patient-reported outcomes assessed at multiple time points up to 12 months and annual follow-up for long-term outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Signed informed consent
* Age ≥ 18 years
* Pathologically confirmed diagnosis of colon or rectal cancer
* Mentally alert and capable of communication
* Willing to participate in follow-up, with an estimated life expectancy of more than 6 months
* Cancer stage IIa, IIb, or IIIa

Exclusion Criteria:

* Nutritional risk screening score of mPG-SGA \< 2 or NRS-2002 \< 3
* Diagnosed with AIDS
* History of organ transplantation
* Pregnant or breastfeeding women
* Concurrent participation in another interventional clinical trial
* Inability to care for oneself independently
* Inability to engage in physical activity during the perioperative period
* Severe comorbid conditions (e.g., uncontrolled cardiovascular disease, severe hepatic or renal dysfunction)
* Known allergy or intolerance to components of the nutritional supplements used in the study

Where it's running

• Xi 'an Jiaotong University
  Xi'an, Shaanxi, China Recruiting

Study contacts

• Study coordinator: Xiaoqin Luo, Ph.D
• Email: luoxiaoqin2012@xjtu.edu.cn
• Phone: +8618802932796

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.