Sex Differences in BDNF Response to a Maximal Exercise Test

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will measure circulating BDNF levels before and after a maximal exercise test in healthy young adults to see if there are sex-related differences. The study focuses on how exercise may boost BDNF, a protein linked to learning and memory. By comparing responses between males and females, the trial aims to clarify whether sex influences the brain-related benefits of acute exercise. The design is observational in terms of the biomarker response to a single exercise bout, conducted at McMaster University in Hamilton, Ontario.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Between the ages of 18 and 35

Exclusion Criteria:

* presence of type 2 diabetes
* history of hypoglycaemia
* history of concussion(s) with persistent symptoms
* presence of major depressive disorder
* history of cardiovascular events requiring hospitalization (i.e., heart attack, stroke)
* presence of respiratory disease (e.g. asthma)
* pre-existing injuries that prevent aerobic exercise participation.

Where it's running

• McMaster University
  Hamilton, Ontario, Canada Recruiting

Study contacts

• Principal investigator: Jeremy J Walsh, PhD — McMaster University
• Study coordinator: Jeremy J Walsh, PhD
• Email: walshj18@mcmaster.ca
• Phone: 905-525-9140

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.