Sensory nerve tests after finger nerve injury
Official title: Investigation of the Correlation of Sensory Neurography Findings and S2PD Measurements After Digital Nerve Injury
Run by Karolinska Institutet · NCT07904286 · Data updated 2026-11-12
This study tests whether neurophysiological measurements can reflect finger sensation changes after digital nerve injury, using patients as their own controls.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 60 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 2 sites (Stockholm and 1 other locations) |
| Status | Recruiting |
| Started | September 28, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | October 29, 2026 |
| Trial ID | NCT07904286 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 21 to 59 with a digital nerve injury at the base or middle phalanx of digits II–IV that occurred one year or more prior to enrollment.
✕Probably not a fit
Individuals with neurologic or cognitive disorders, severe psychiatric illness, ongoing drug abuse, inability to understand Swedish, prior carpal tunnel history, or intolerance to electrical stimulation may not benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cross-sectional study compares neurophysiological data with static two-point discrimination (S2PD) results in fingers with prior digital nerve injuries. Participants will undergo neurophysiology testing and S2PD on the injured finger and the corresponding uninjured finger, serving as internal controls. Before data collection, a test-retest reliability check will be done in ten participants to ensure consistent measurements. The researchers aim to determine if objective neurophysiological measures (amplitude and area of nerve potentials) correlate with discriminative sensory function and whether these measurements could provide a reliable, complementary assessment to S2PD.
Why it matters
Potential benefit: If successful, neurophysiological measurements could offer an objective way to assess residual nerve function and improve understanding of sensory recovery after digital nerve injury.
How similar studies have gone: Previous work has explored neurophysiological methods to measure residual nerve function, but using these measures to directly correlate with S2PD in digital nerve injuries is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Injury: One year or more prior to inclusion Injured finger: digit II, III or radial dig IV Level of injury: base or middle phalanx Age at injury\>20 Age at inclusion\<60 Exclusion Criteria: Neurologic disease Dementia Cognitive disability Severe psychiatric disorder (not be able to participate) Ongoing drug abuse Not understanding swedish language History of carpal tunnel syndrome Negative experience of electric stimulation
Where it's running
-
South General Hospital
Stockholm, Sweden Recruiting -
Karolinska Institutet Södersjukhuset, Department of clinical research and education
Stockholm, Sweden Not yet recruiting
Study contacts
- Principal investigator: Cecilia Mellstrand-Navarro, Ass. prof — Karolinska Institutet Södersjukhuset, Department of clinical research and education
- Study coordinator: Carin Carlsson, MD
- Email: carin.carlsson@regionstockholm.se
- Phone: 0046812361000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Using electrical stimulation to enhance nerve healing after surgery for digital nerve injuries
This study tests if using electrical stimulation during surgery can help people with finger nerve injuries heal faster and better.
-
Comparing surgical and non-surgical treatments for finger nerve injuries
This study is testing whether surgery or a cast works better for helping adults with finger nerve injuries recover and regain feeling and movement.
-
Cognitive Rehabilitation of Everyday Goals With GMT: How Different Ways of Delivery Work
This study tests Goal Management Training to see if a Swedish version helps adults with acquired brain injury or chronic pain improve practical goal-directed thinking and daily functioning.
-
National Highly Specialized Care for Severe Self-Harm and Eating Disorders in Swedish Youth
This observational study tests how well NHV, a highly specialized care program, works for children and teens with severe self-harm or eating disorders by asking patients and their parents about their experiences and what changes they notice.
-
Specialist Supportive Clinical Management for teens with anorexia or atypical anorexia
This study tests a teen-focused SSCM approach to help 13-17 year-olds with anorexia nervosa or atypical anorexia nervosa when other treatments haven’t worked or can’t be used.
-
National Highly Specialized Care for adults with treatment-resistant self-harm and eating disorders (Substudy 1)
This study tests how people with severe, hard-to-turge self-harm or eating disorders in Sweden experience NHV care and whether the treatment helps with symptoms and daily functioning.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.