Self-sampling to improve cervical cancer screening attendance
Official title: Cervical Cancer Prevention Using Self-sampling and Human Papillomavirus Detection
Run by The Institute of Molecular and Translational Medicine, Czech Republic · NCT04226313 · Data updated 2026-11-12
This study is testing if sending self-sampling kits by mail, through gynecologists, or general practitioners can help more women in the Czech Republic get screened for cervical cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 65 Years |
| Sex | Women only |
| Enrollment | 15000 (estimated) |
| Sponsor | The Institute of Molecular and Translational Medicine, Czech Republic Academic / other |
| Locations | 1 site (Olomouc) |
| Status | Recruiting |
| Started | September 23, 2019 |
| Main results expected | December 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | March 23, 2026 |
| Trial ID | NCT04226313 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women aged 30-65 who have not participated in cervical cancer screening for at least three years and reside in the Czech Republic.
✕Probably not a fit
Patients who are pregnant, have no sexual intercourse experience, or have undergone a hysterectomy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial evaluates the effectiveness of self-sampling and HPV testing to increase cervical cancer screening participation among under-screened women in the Czech Republic. It will compare three methods of providing self-sampling devices: by mail, through gynecologists, and via general practitioners. The study aims to determine the acceptability of self-sampling and its impact on screening attendance, while also analyzing sociodemographic factors. The goal is to address the low participation rates in cervical cancer screening and improve women's health outcomes.
Why it matters
Potential benefit: If successful, this approach could significantly increase cervical cancer screening rates and reduce the incidence of cervical cancer among under-screened women.
How similar studies have gone: Previous studies in several European countries have shown success with self-sampling approaches to increase cervical cancer screening attendance.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women with age 30-65 years; for arm A women \> 65 years are allowed * Women live in the Czech Republic. * Women who have not participate in cervical cancer screening program in the Czech Republic for at least 3 years (Arm B and C). * Women with completed informed consent. * Women capable of self-sampling of cervicovaginal swab. Exclusion Criteria: * Pregnant women. * Women with no sexual intercourse experience. * Women after hysterectomy including cervix.
Where it's running
-
University Hospital Olomouc
Olomouc, Czechia Recruiting
Study contacts
- Study coordinator: Marian Hajduch, MD, PhD.
- Email: marian.hajduch@upol.cz
- Phone: +420 585 632 083
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.