Self-management program to reduce epilepsy burden in Ugandans.
Official title: Self-Management Intervention for Reducing Stroke Burden Among Ugandans With Epilepsy
Run by Makerere University · NCT06139198 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing a new self-management program for adults with epilepsy in Uganda to see if it can help them feel better and have fewer seizures compared to standard care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 188 (estimated) |
| Sponsor | Makerere University Academic / other |
| Locations | 1 site (Kampala) |
| Trial ID | NCT06139198 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older with a clinical diagnosis of epilepsy who have experienced at least one seizure in the past six months.
✕Probably not a fit
Patients with dementia, those who are pregnant, or individuals unable to participate in study procedures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial evaluates the effectiveness of a self-management intervention called SMART-U for adults with epilepsy in Uganda, comparing it to enhanced treatment as usual (eTAU). Participants will be randomly assigned to either the SMART-U program, which includes group sessions and follow-up support via phone, or to eTAU, which consists of standard care supplemented with educational materials. The study aims to improve quality of life, reduce seizure frequency, and enhance overall health outcomes for individuals living with epilepsy. The intervention will also assess the validity of self-reported seizure occurrences through mobile phone text messages.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the quality of life and seizure management for patients with epilepsy in Uganda.
How similar studies have gone: Other studies have shown promise in using self-management interventions for epilepsy, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Participants will have a clinical diagnosis of epilepsy documented with at least two outpatients visits; this will ensure that the study participants have been taking ASMs but still getting breakthrough seizures. 2. ≥ age 18, attending the neurology clinics, 3. Be able to provide written informed consent by the study participant or immediate caregiver/legal guardian, 4. Ability to participate in study procedures, this is due to time required to attend and participate in the scheduled sessions which may last between 45mins - 1 hour. 5. and have had at least 1 seizure in the past 6 months. 6. Owning a mobile phone either by the PWE or immediate caregiver Exclusion Criteria: 1. Participants with dementia 2. Participants who are pregnant (given the likely need of different and more intensive treatments among pregnant PWE that may affect their ability to participate in the SMART-U sessions regularly. 3. Or those who are unable to participate in study procedures.
Where it's running
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Mulago National Referral and Teaching Hospital
Kampala, Uganda Recruiting
Study contacts
- Principal investigator: Mark Kaddumukasa, MD — Makerere University
- Study coordinator: Doreen Birungi, BA
- Email: bdoreen112@gmail.com
- Phone: +256772474096
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.