Self-administered screening for cervical cancer in Uganda
Prevention and Early Detection of Cervical Cancer Through Self-Administered Screening in the Community
University of California, San Francisco · NCT04927650
This study is testing if women in rural Uganda will accept and complete self-collected HPV tests to help find cervical cancer early.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3200 (estimated) |
| Ages | 25 Years to 49 Years |
| Sex | Female |
| Sponsor | University of California, San Francisco (other) |
| Locations | 1 site (Kampala) |
| Trial ID | NCT04927650 on ClinicalTrials.gov |
What this trial studies
This study focuses on the prevention and early detection of cervical cancer through self-administered HPV screening in rural Uganda. It aims to evaluate the acceptance of self-collected HPV testing among women and to track the completion of the cervical cancer screening process. Participants will receive a specimen kit for HPV sample collection and complete questionnaires to assess their experiences. The study also seeks to estimate the prevalence of high-risk HPV and cervical intraepithelial neoplasia in the community.
Who should consider this trial
Good fit: Ideal candidates are women aged 25-49 residing in Kiboga, Kyankwanzi, or Hoima districts of Uganda who are participating in community health campaigns.
Not a fit: Patients showing clinical signs and symptoms of cervical cancer will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve early detection and prevention of cervical cancer among women in rural Uganda.
How similar studies have performed: Other studies have shown promise in using self-collected HPV testing for cervical cancer screening, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women in the three Ugandan districts (Kiboga, Kyankwanzi and Hoima) who access screening during the community health campaigns * Age 25-49 years * Resident in the study district * Provision of informed consent Exclusion Criteria: * Clinical signs and symptoms of cancer of the cervix
Where this trial is running
Kampala
- Makerere University College of Health Sciences School of Medicine — Kampala, Uganda (RECRUITING)
Study contacts
- Principal investigator: Jeffrey Martin, MD, MPH — University of California, San Francisco
- Study coordinator: Jeffrey Martin, MD, MPH
- Email: Jeffrey.Martin@ucsf.edu
- Phone: (415) 514-8010
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cervical Carcinoma, Human Papillomavirus-Related Carcinoma, Cervical Cancer Screening, Human Papillomavirus, HPV