Segeberg registry for mitral clip (M-TEER) in severe mitral regurgitation
Official title: A Prospective Follow-up Assessment in Bad Segeberg With Patients With Severe Mitral Regurgitation Undergoing Mitral Edge-to-edge Repair (M-TEER).
Run by Segeberger Kliniken GmbH · NCT07045753 · Data updated 2026-11-12
This registry follows people with severe mitral regurgitation who get a mitral valve clip (M-TEER) at the Segeberg heart center to see how they do over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Segeberger Kliniken GmbH Academic / other |
| Locations | 1 site (Bad Segeberg, Schleswig-Holstein) |
| Status | Recruiting |
| Started | January 1, 2011 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2032 |
| Registry record updated | July 1, 2025 |
| Trial ID | NCT07045753 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with severe mitral regurgitation who undergo transcatheter edge-to-edge repair (M-TEER) at the Herzzentrum Segeberger Kliniken.
✕Probably not a fit
Patients who do not undergo M-TEER, have only mild or moderate MR, or who are treated at other hospitals will not be eligible and are unlikely to gain direct benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, single-center registry enrolling all patients treated with transcatheter edge-to-edge mitral repair (M-TEER) at the Heart Center, Bad Segeberg. Patients undergo a routine clinical follow-up schedule that includes clinical visits and imaging over the long term. Procedural details, in-hospital outcomes, and subsequent clinical events are recorded in a database. The registry aims to capture real-world safety, durability of repair, and patient-centered outcomes after M-TEER.
Why it matters
Potential benefit: If successful, the registry could improve understanding of long-term safety and real-world outcomes after M-TEER and help refine care for patients with severe MR.
How similar studies have gone: Randomized trials and multiple registries of M-TEER have reported clinical benefit in selected patients, so this registry builds on established evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with severe MR undergoing M-TEER Exclusion Criteria: * None
Where it's running
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Herzzentrum Segeberger Kliniken GmbH
Bad Segeberg, Schleswig-Holstein, Germany Recruiting
Study contacts
- Study coordinator: Arief Kurniadi, MD
- Email: arief.kurniadi@segebergerkliniken.de
- Phone: +4945512802
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Capstan TMVR Feasibility for Mitral Regurgitation
This early feasibility study tests the Capstan Compass Robotic System to replace the mitral valve in adults with symptomatic, moderate-to-severe or severe mitral regurgitation who aren’t candidates for surgical repair or standard edge-to-edge repair.
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Transcatheter repair for atrial functional mitral regurgitation in high-risk patients
This trial tests whether adding a catheter-based mitral valve repair (TEER) to optimized medical therapy helps adults with atrial functional MR who are at high surgical risk.
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This trial will test the MitraFix transcatheter mitral valve system to see if it can be safely implanted and reduce severe leaky mitral valves in adults at high risk for open-heart surgery.
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DELINEATE-Prospective: AI-assisted echocardiogram analysis for valve disease
This project will test whether an AI system can automatically analyze echocardiograms to help doctors detect valve problems in adults who get heart ultrasounds.
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This study looks at patients with moderate to severe mitral regurgitation to see what factors might affect their health outcomes and help doctors make better treatment decisions.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.