Second hip fracture risk in Chinese patients with osteoporotic hip fractures
Official title: Second Hip Fracture Evaluation in Chinese Elderly Patients Using Quantitative Computed Tomography
Run by Beijing Jishuitan Hospital · NCT03461237 · Data updated 2026-11-12
This project will see if CT-based measurements of bone and muscle can predict second hip fractures in older adults who have already had an osteoporotic hip fracture.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 50 Years to 95 Years |
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | Beijing Jishuitan Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | May 1, 2017 |
| Main results expected | May 2026 |
| Study ends | November 2026 |
| Registry record updated | August 17, 2025 |
| Trial ID | NCT03461237 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 47 or older with a surgically treated osteoporotic femoral neck or trochanteric hip fracture who can undergo CT imaging and provide informed consent.
✕Probably not a fit
Patients under 47, those with non-surgical repairs, pathologic or violence-related fractures, or with bilateral hip implants or a contralateral hip replacement are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational study enrolls patients with surgically treated osteoporotic femoral neck or trochanteric hip fractures at Beijing Jishuitan Hospital. Participants will undergo quantitative CT (QCT) of the proximal femur to measure volumetric bone mineral density, bone structure, and surrounding muscle, with centralized image interpretation and quality control. The investigators will compare second-hip fracture rates by sex and fracture type and test whether QCT-derived metrics improve prediction of subsequent contralateral hip fractures. The study also aims to identify structural and muscle differences between femoral neck and trochanteric fractures during the healing process.
Why it matters
Potential benefit: If successful, the results could help clinicians identify patients at high risk for a second hip fracture so they can target prevention and closer monitoring.
How similar studies have gone: Prior work shows QCT measures of volumetric BMD and bone structure relate to fracture risk, but applying QCT specifically to predict second hip fractures has been less well studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * a:Osteoporotic patients b:Osteoporotic hip fracture patients (femoral neck fracture and femoral trochanteric fracture) c: Be willing to and be able to join in the study and sighed the informed consent Exclusion Criteria: * a:Under 47years old b:Non-surgical repair of hip fracture c:Pathologic fracture d:Violence-related trauma e:Bilateral hip implants or have hip replacement on the non-fractured side
Where it's running
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Beijing ji shui tan hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Principal investigator: Xiaoguang Cheng, MD — department of radiology, Beijing Jishuitan Hospital
- Study coordinator: Xiaoguang Cheng, MD
- Email: xiao65@263.net
- Phone: 0086-010-58516947
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.