Clinical trial Recruiting at 1 site Observational Ages 18 and up

Screening for intracranial atherosclerosis using fundus imaging

Official title: Intracranial Atherosclerosis Screen Based on Retinal Imaging Characteristic

Run by Xuanwu Hospital, Beijing · NCT06610578 · Data updated 2026-11-12

This study is testing if a simple eye exam can help find early signs of a serious condition that causes strokes in people, especially in the Asian population.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment2100 (estimated)
SponsorXuanwu Hospital, Beijing
Academic / other
Locations1 site (Beijing, None Selected)
StatusRecruiting
StartedSeptember 5, 2024
Main results expectedSeptember 2026
Study endsSeptember 2027
Registry record updatedOctober 31, 2024
Trial IDNCT06610578 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old who have recently completed head and neck imaging examinations.

Probably not a fit

Patients with poor quality fundus images, intracranial mass lesions, severe organ diseases, or those who are pregnant or lactating may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on intracranial atherosclerosis stenosis (ICAS), a major cause of ischemic stroke, particularly in the Asian population. It aims to explore the effectiveness of fundus imaging as a non-invasive screening tool for early detection of ICAS, which could lead to timely interventions and improved patient outcomes. The study will include patients who have undergone recent imaging examinations like DSA, CTA, or MRA, and will assess their ability to cooperate with follow-up fundus examinations. By identifying patients at risk, the study seeks to enhance early warning and prevention strategies for stroke.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection and prevention of strokes in patients with intracranial atherosclerosis.

How similar studies have gone: While there are promising screening tools for ICAS, this specific approach using fundus imaging is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. The age is above 18 years old;
2. Complete head and neck DSA, CTA, MRA or HR-MRI examination within 2 weeks;
3. He/She can cooperate with follow-up fundus examination with free movement;
4. Signed informed consent.

Exclusion Criteria:

1. Poor quality of fundus images;
2. With intracranial mass lesions;
3. With severe heart, liver and kidney diseases;
4. With pregnancy and lactation.

Where it's running

  • Xuanwu Hospital, Capital Medical University
    Beijing, None Selected, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.