Screening for intracranial atherosclerosis using fundus imaging
Official title: Intracranial Atherosclerosis Screen Based on Retinal Imaging Characteristic
Run by Xuanwu Hospital, Beijing · NCT06610578 · Data updated 2026-11-12
This study is testing if a simple eye exam can help find early signs of a serious condition that causes strokes in people, especially in the Asian population.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2100 (estimated) |
| Sponsor | Xuanwu Hospital, Beijing Academic / other |
| Locations | 1 site (Beijing, None Selected) |
| Status | Recruiting |
| Started | September 5, 2024 |
| Main results expected | September 2026 |
| Study ends | September 2027 |
| Registry record updated | October 31, 2024 |
| Trial ID | NCT06610578 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old who have recently completed head and neck imaging examinations.
✕Probably not a fit
Patients with poor quality fundus images, intracranial mass lesions, severe organ diseases, or those who are pregnant or lactating may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on intracranial atherosclerosis stenosis (ICAS), a major cause of ischemic stroke, particularly in the Asian population. It aims to explore the effectiveness of fundus imaging as a non-invasive screening tool for early detection of ICAS, which could lead to timely interventions and improved patient outcomes. The study will include patients who have undergone recent imaging examinations like DSA, CTA, or MRA, and will assess their ability to cooperate with follow-up fundus examinations. By identifying patients at risk, the study seeks to enhance early warning and prevention strategies for stroke.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and prevention of strokes in patients with intracranial atherosclerosis.
How similar studies have gone: While there are promising screening tools for ICAS, this specific approach using fundus imaging is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. The age is above 18 years old; 2. Complete head and neck DSA, CTA, MRA or HR-MRI examination within 2 weeks; 3. He/She can cooperate with follow-up fundus examination with free movement; 4. Signed informed consent. Exclusion Criteria: 1. Poor quality of fundus images; 2. With intracranial mass lesions; 3. With severe heart, liver and kidney diseases; 4. With pregnancy and lactation.
Where it's running
-
Xuanwu Hospital, Capital Medical University
Beijing, None Selected, China Recruiting
Study contacts
- Study coordinator: Gao
- Email: gychina163@163.com
- Phone: 86+01083199439
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.