Screening for chronic liver diseases in the general population

Non-invasive Screening for Chronic Liver Diseases in the General Population. A Prospective Study

Not applicable Interventional University Hospital, Montpellier · NCT06366425

This study is testing a new screening program to help find people at risk for serious liver problems using a blood test and a special scan to improve their care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment260 (estimated)
Ages40 Years and up
SexAll
SponsorUniversity Hospital, Montpellier Academic / other
Locations1 site (Montpellier)
Trial IDNCT06366425 on ClinicalTrials.gov

What this trial studies

This study aims to improve the care of patients with chronic liver diseases by implementing a screening program in primary care settings. It focuses on assessing liver fibrosis using a combination of a blood test (FIB-4 score) and a non-invasive procedure (Fibroscan). The goal is to identify individuals at risk for advanced liver fibrosis and raise awareness about chronic liver diseases among healthcare providers and the general public. By refining the screening process, the study seeks to enhance patient outcomes and facilitate appropriate care for those affected.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 40 and older who do not have known liver pathologies but possess at least one risk factor for chronic liver disease.

Not a fit: Patients who have had a Fibroscan in the last 12 months or those with known liver diseases will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to earlier detection and better management of chronic liver diseases, ultimately improving patient outcomes.

How similar studies have performed: Previous studies have shown success with similar non-invasive screening approaches for liver diseases, indicating the potential effectiveness of this methodology.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 40 years
* Without known liver pathologies
* Having at least one risk factor for chronic liver disease: risky consumption of alcoholic beverages according to the AUDIT questionnaire, the presence of metabolic syndrome, diabetes or a risk factor for viral hepatitis B, D or C.

Exclusion Criteria:

* Fibroscan already performed in the last 12 months
* Failure to collect express oral consent
* Patient not affiliated with or not benefiting from a national health insurance scheme
* Patient protected by law
* Patient under guardianship or curatorship
* Patient deprived of liberty
* Pregnant or breastfeeding woman

Where this trial is running

Montpellier

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Fibrosis, LiverNon-alcoholic fatty liver diseaseHepatocellular carcinomaChronic liver diseasesLinkage to careFibrosis researchNon-invasive diagnosisFIB-4
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.