Screening blood biomarkers for osteoarthritis diagnosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will collect blood samples from patients with diagnosed or suspected osteoarthritis attending the orthopedic outpatient department of a tertiary hospital in Xinxiang. Diagnostic and differential tests, including X-ray and MRI, will be used alongside laboratory analysis to compare previously reported candidate biomarkers with clinical diagnoses. The goal is to identify biomarkers that show reliable validity and reproducibility for early detection or differentiation of OA. Participants must meet inclusion/exclusion criteria and complete required imaging and follow-up visits.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged between 40 and 70 years (inclusive);
2. Joint pain or stiffness lasting for no less than 3 months;
3. Voluntary participation with signed informed consent.

Exclusion Criteria:

1. Combined with other severe joint diseases, such as rheumatoid arthritis, gout, etc.;
2. Suffering from severe systemic diseases, such as heart failure, malignant tumors and others;
3. Received joint surgery within the past 3 months or taking medications that may affect the progression of osteoarthritis;
4. Individuals with cognitive dysfunction who are unable to cooperate with the research procedures;
5. Failure to complete X-ray, MRI examination or follow-up visits as required.

Where it's running

• The First Affiliated Hospital of Henan Medical University
  Xinxiang, Henan, China Recruiting

Study contacts

• Study coordinator: Wenjie Ren
• Email: 157121431@qq.com
• Phone: 8618937302619

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.