Screening and assessment for older patients with ovarian cancer
Official title: FRAGINOC Study: The Impact of FRAilty Screening and Geriatric Assessment and Intervention in Older Patients With Epithelial Ovarian Cancer
Run by Odense University Hospital · NCT05810701 · Data updated 2026-11-12
This study is testing whether a special assessment and personalized exercise program can help older patients with ovarian cancer get better treatment options compared to standard care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 70 Years to 120 Years |
| Sex | Women only |
| Enrollment | 300 (estimated) |
| Sponsor | Odense University Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 5 sites (Odense, Region of South Denmark and 4 other locations) |
| Status | Recruiting |
| Started | February 1, 2023 |
| Main results expected | February 1, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | April 12, 2023 |
| Trial ID | NCT05810701 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are older adults newly diagnosed with ovarian cancer who can understand written and oral Danish.
✕Probably not a fit
Patients with other active cancers in the past five years or severe psychiatric diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on older patients diagnosed with epithelial ovarian cancer, aiming to improve treatment outcomes through a comprehensive geriatric assessment (CGA) and individualized physical training. The research will compare the effectiveness of this approach against standard care, particularly in increasing the number of patients eligible for interval debulking surgery. Additionally, it will evaluate the performance of various validated screening tests to identify frailty and immunodeficiency in these patients. The study seeks to address the gap in treatment for frail older patients who are often undertreated or over-treated due to their age and health status.
Why it matters
Potential benefit: If successful, this approach could lead to better treatment outcomes and reduced complications for older patients with ovarian cancer.
How similar studies have gone: Other studies have indicated the potential benefits of geriatric assessments in oncology, but this specific approach for ovarian cancer in older patients is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Newly diagnosed ovarian cancer * Capable of understanding written and oral danish Exclusion Criteria: * Other active cancers in the preceding 5 years * Severe psychiatric disease Patients referred to primary debulking surgery will be followed in a observational design
Where it's running
-
Odense University Hospital
Odense, Region of South Denmark, Denmark Recruiting -
Vejle Hospital
Vejle, Region of South Denmark, Denmark Recruiting -
Zealand University Hospital
Roskilde, Region Sjælland, Denmark Recruiting -
Copenhagen University Hospital Rigshospitalet
Copenhagen, The Capital Region of Denmark, Denmark Recruiting -
Herlev and Gentofte Hospital
Herlev, The Capital Region of Denmark, Denmark Recruiting
Study contacts
- Study coordinator: Tine Henrichsen Schnack, PhD
- Email: tine.henrichsen.schnack@rsyd.dk
- Phone: +4527284828
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.